Recombinant人Cysteine Dioxygenase Type 1 protein (ab87691)

概述

描述

  • 性质
    Recombinant
  • 来源
    Escherichia coli
  • 氨基酸序列
    • 种属
      Human
    • 序列
      MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSHMEQ TEVLKPRTLA DLIRILHQLF AGDEVNVEEV QAIMEAYESD PTEWAMYAKF DQYRYTRNLV DQGNGKFNLM ILCWGEGHGS SIHDHTNSHC FLKMLQGNLK ETLFAWPDKK SNEMVKKSER VLRENQCAYI NDSVGLHRVE NISHTEPAVS LHLYSPPFDT CHAFDQR
    • 氨基酸
      1 to 170

技术指标

Our Abpromise guarantee covers the use of ab87691 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

  • 纯度
    > 90 % SDS-PAGE.
    Purified by using conventional chromatography techniques.
  • 形式
    Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 10% Glycerol, 20mM Tris, 1mM DTT, pH 8

常规信息

  • 别名
    • CDO
    • CDO 1
    • CDO I
    • CDO-I
    • Cdo1
    • CDO1_HUMAN
    • CDOI
    • Cysteine dioxygenase type 1
    • Cysteine dioxygenase type I
    • Cytosolic cysteine dioxygenase
    see all
  • 功能
    Initiates several important metabolic pathways related to pyruvate and several sulfurate compounds including sulfate, hypotaurine and taurine. Critical regulator of cellular cysteine concentrations. Has an important role in maintaining the hepatic concentation of intracellular free cysteine within a proper narrow range.
  • 组织特异性
    Highly expressed in liver and placenta. Low expression in heart, brain and pancreas. Also detected in hepatoblastoma HepG2 cells.
  • 通路
    Organosulfur biosynthesis; taurine biosynthesis; hypotaurine from L-cysteine: step 1/2.
  • 序列相似性
    Belongs to the cysteine dioxygenase family.
  • 翻译后修饰
    The thioether cross-link between Cys-93 and Tyr-157 plays a structural role through stabilizing the Fe(2+) ion, and prevents the production of highly damaging free hydroxyl radicals by holding the oxygen radical via hydroxyl hydrogen.
  • Information by UniProt

Recombinant Human Cysteine Dioxygenase Type 1 protein 图像

  • ab87691 on 15% SDS-PAGE (3µg)

Recombinant Human Cysteine Dioxygenase Type 1 protein (ab87691)参考文献

ab87691 has not yet been referenced specifically in any publications.

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