Recombinant人Cyclin H protein (ab95351)

概述

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • 种属Human
    • 序列MGSSHHHHHH SSGLVPRGSH MYHNSSQKRH WTFSSEEQLA RLRADANRKF RCKAVANGKV LPNDPVFLEP HEEMTLCKYY EKRLLEFCSV FKPAMPRSVV GTACMYFKRF YLNNSVMEYH PRIIMLTCAF LACKVDEFNV SSPQFVGNLR ESPLGQEKAL EQILEYELLL IQQLNFHLIV HNPYRPFEGF LIDLKTRYPI LENPEILRKT ADDFLNRIAL TDAYLLYTPS QIALTAILSS ASRAGITMES YLSESLMLKE NRTCLSQLLD IMKSMRNLVK KYEPPRSEEV AVLKQKLERC HSAELALNVI TKKRKGYEDD DYVSKKSKHE EEEWTDDDLV ESL

技术指标

Our Abpromise guarantee covers the use of ab95351 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

  • 纯度> 90 % SDS-PAGE.
    ab95351 is purified using conventional chromatography techniques.
  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Preservative: None
    Constituents: 30% Glycerol, 0.1M Sodium chloride, 20mM Tris HCl, 2mM EDTA, 2mM DTT, pH 8.0

常规信息

  • 别名
    • 6330408H09Rik
    • AI661354
    • AV102684
    • AW538719
    • CAK
    • CAK complex subunit
    • ccnh
    • CCNH_HUMAN
    • CDK activating kinase
    • CDK activating kinase complex subunit
    • Cyclin dependent kinase activating kinase
    • cyclin dependent kinase activating kinase complex subunit
    • Cyclin H
    • Cyclin-H
    • CyclinH
    • MO15 associated protein
    • MO15-associated protein
    • p34
    • p36
    • p37
    see all
  • 功能Regulates CDK7, the catalytic subunit of the CDK-activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminus domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II. Its expression and activity are constant throughout the cell cycle.
  • 序列相似性Belongs to the cyclin family. Cyclin C subfamily.
  • 细胞定位Nucleus.
  • Information by UniProt

Recombinant Human Cyclin H protein 图像

  • 15% SDS-PAGE showing ab95351 at approximately 40 kDa (3 µg).

Recombinant Human Cyclin H protein (ab95351)参考文献

ab95351 has not yet been referenced specifically in any publications.

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