Recombinant人Cyclin G protein (ab116149)

概述

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • AccessionP51959
    • 种属Human
    • 序列MGSSHHHHHHSSGLVPRGSHMIEVLTTTDSQKLLHQLNALLEQESRCQPK VCGLRLIESAHDNGLRMTARLRDFEVKDLLSLTQFFGFDTETFSLAVNLL DRFLSKMKVQPKHLGCVGLSCFYLAVKSIEEERNVPLATDLIRISQYRFT VSDLMRMEKIVLEKVCWKVKATTAFQFLQLYYSLLQENLPLERRNSINFE RLEAQLKACHCRIIFSKAKPSVLALSIIALEIQAQKCVELTEGIECLQKH SKINGRDLTFWQELVSKCLTEYSSNKCSKPNVQKLKWIVSGRTARQLKHS YYRITHLPTIPEMVP
    • 分子量36 kDa including tags
    • 氨基酸1 to 295
    • 标签His tag N-Terminus

技术指标

Our Abpromise guarantee covers the use of ab116149 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Mass Spectrometry

    SDS-PAGE

  • 质谱法
    MALDI-TOF
  • 纯度> 85 % SDS-PAGE.
    ab116149 was purified using conventional chromatography.
  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 1.17% Sodium chloride, 0.08% DTT, 50% Glycerol, 0.32% Tris HCl

常规信息

  • 别名
    • CCNG
    • CCNG 1
    • CCNG1
    • CCNG1_HUMAN
    • CYCG1
    • Cyclin G
    • Cyclin G1
    • Cyclin-G
    • Cyclin-G1
    see all
  • 功能May play a role in growth regulation. Is associated with G2/M phase arrest in response to DNA damage. May be an intermediate by which p53 mediates its role as an inhibitor of cellular proliferation.
  • 组织特异性High levels in skeletal muscle, ovary, kidney and colon.
  • 序列相似性Belongs to the cyclin family. Cyclin G subfamily.
  • 发展阶段Very low levels in normal cells during G1 phase, which increase as cells enter the S phase and stay high throughout the S and G2/M phases. In breast cancer cells consistent high levels are found throughout the cell cycle.
  • 细胞定位Nucleus. DNA replication foci after DNA damage.
  • Information by UniProt

Recombinant Human Cyclin G protein 图像

  • 15% SDS-PAGE showing ab116149 3ug.

Recombinant Human Cyclin G protein (ab116149)参考文献

ab116149 has not yet been referenced specifically in any publications.

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