- 来源Baculovirus infected Sf9 cells
- 分子量73 kDa including tags
- 氨基酸1 to 410
Our Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
- 纯度> 90
Purity tested by densitometry.
Concentration information loading...
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
Constituents: 25% Glycerol, 0.79% Tris HCl, 0.88% Sodium chloride, 0.31% Glutathione, 0.003% EDTA, 0.003% DTT, 0.002% PMSF
- 功能Essential for the control of the cell cycle at the G1/S (start) transition.
- 组织特异性Highly expressed in testis and placenta. Low levels in bronchial epithelial cells.
- 序列相似性Belongs to the cyclin family. Cyclin E subfamily.
- 翻译后修饰Phosphorylation of Thr-395 by GSK3 and of Ser-399 by CDK2 accelerates degradation via the ubiquitin proteasome pathway. Phosphorylated upon DNA damage, probably by ATM or ATR.
Information by UniProt
Recombinant Human Cyclin E1 protein 图像
Recombinant Human Cyclin E1 protein (ab119719)参考文献
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"