重组人CXCL16蛋白(ab50175)
Key features and details
- Expression system: Escherichia coli
- Purity: > 98% SDS-PAGE
- Active: Yes
- Suitable for: SDS-PAGE, Functional Studies
描述
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产品名称
重组人CXCL16蛋白
参阅全部 CXCL16 蛋白酶 -
生物活性
Biological Activity : Determined by it's ability to chemoattract activated lymphocytes using a concentration of 1.0-100.0 ng/ml.
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纯度
> 98 % SDS-PAGE.
Endotoxin level is less than 0.1 ng per g (1EU/g). -
表达系统
Escherichia coli -
蛋白长度
Protein fragment -
无动物成分
No -
性质
Recombinant -
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种属
Human -
序列
NEGSVTGSCY CGKRISSDSP PSVQFMNRLR KHLRAYHRCL YYTRFQLLSW SVCGGNKDPW VQELMSCLDL KECGHAYSGI VAHQKHLLP -
氨基酸
49 to 137
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技术指标
Our Abpromise guarantee covers the use of ab50175 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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应用
SDS-PAGE
Functional Studies
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形式
Lyophilized -
Concentration information loading...
制备和贮存
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稳定性和存储
Shipped at 4°C. The lyophilized protein is stable for a few weeks at room temperature. Store at -20°C long term.
This product is an active protein and may elicit a biological response in vivo, handle with caution.
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复溶Reconstitute to 1mg/ml in sterile water.
常规信息
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别名
- C-X-C motif chemokine 16
- Chemokine (C X C motif) ligand 16
- Chemokine, CXC motif, ligand 16
see all -
功能
Acts as a scavenger receptor on macrophages, which specifically binds to OxLDL (oxidized low density lipoprotein), suggesting that it may be involved in pathophysiology such as atherogenesis (By similarity). Induces a strong chemotactic response. Induces calcium mobilization. Binds to CXCR6/Bonzo. -
组织特异性
Expressed in T-cell areas. Expressed in spleen, lymph nodes, lung, kidney, small intestine and thymus. Weak expression in heart and liver and no expression in brain and bone marrow. -
序列相似性
Belongs to the intercrine alpha (chemokine CxC) family. -
翻译后修饰
Glycosylated. -
细胞定位
Cell membrane. Secreted. Also exists as a soluble form. - Information by UniProt
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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Datasheet download
文献 (1)
ab50175 被引用在 1 文献中.
- Abu El-Asrar AM et al. Evaluation of Proteoforms of the Transmembrane Chemokines CXCL16 and CX3CL1, Their Receptors, and Their Processing Metalloproteinases ADAM10 and ADAM17 in Proliferative Diabetic Retinopathy. Front Immunol 11:601639 (2020). PubMed: 33552057