The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
补充说明ab112415 is best use within three months from the date of receipt.
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Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00 Constituents: 0.79% Tris HCl, 0.31% Glutathione
B cell CLL/lymphoma 11A (zinc finger protein)
B cell CLL/lymphoma 11A (zinc finger protein) isoform 2
B-cell CLL/lymphoma 11A
B-cell lymphoma/leukemia 11A
BCL11A B cell CLL/lymphoma 11A (zinc finger protein) isoform 1
C2H2 type zinc finger protein
COUP TF interacting protein 1
COUP-TF-interacting protein 1
CTIP1, mouse, homolog of
Ecotropic viral integration site 9
Ecotropic viral integration site 9 homolog
Ecotropic viral integration site 9 protein
Ecotropic viral integration site 9 protein homolog
Evi9, mouse, homolog of
Zinc finger protein 856
功能Functions as a myeloid and B-cell proto-oncogene. May play important roles in leukemogenesis and hematopoiesis. An essential factor in lymphopoiesis, is required for B-cell formation in fetal liver. May function as a modulator of the transcriptional repression activity of ARP1.
组织特异性Expressed at high levels in brain, spleen thymus, bone marrow and testis. Expressed in CD34-positive myeloid precursor cells, B-cells, monocytes and megakaryocytes. Expression is tightly regulated during B-cell development.
疾病相关Note=Chromosomal aberrations involving BCL11A may be a cause of lymphoid malignancies. Translocation t(2;14)(p13;q32.3) causes BCL11A deregulation and amplification.
序列相似性Contains 6 C2H2-type zinc fingers.
翻译后修饰Sumoylated by SUMO1.
细胞定位Cytoplasm. Nucleus. Associates with the nuclear body. Colocalizes with SUMO1 and SENP2 in nuclear speckles.