Recombinant人CTDSP1 protein (ab124856)

概述

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • AccessionQ9GZU7
    • 种属Human
    • 序列MGSSHHHHHHSSGLVPRGSHMDSSAVITQISKEEARGPLRGKGDQKSAAS QKPRSRGILHSLFCCVCRDDGEALPAHSGAPLLVEENGAIPKTPVQYLLP EAKAQDSDKICVVIDLDETLVHSSFKPVNNADFIIPVEIDGVVHQVYVLK RPHVDEFLQRMGELFECVLFTASLAKYADPVADLLDKWGAFRARLFRESC VFHRGNYVKDLSRLGRDLRRVLILDNSPASYVFHPDNAVPVASWFDNMSD TELHDLLPFFEQLSRVDDVYSVLRQPRPGS
    • 分子量31 kDa including tags
    • 氨基酸1 to 260
    • 标签His tag N-Terminus

技术指标

Our Abpromise guarantee covers the use of ab124856 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

  • 纯度> 90 % SDS-PAGE.
    ab124856 is purified by proprietary chromatographic techniques and sterile filtered.
  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.02% DTT, 0.32% Tris HCl, 20% Glycerol, 0.58% Sodium chloride

常规信息

  • 别名
    • Carboxy terminal domain RNA polymerase II polypeptide A small phosphatase 1
    • Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1
    • CTD (carboxy terminal domain RNA polymerase II polypeptide A) small phosphatase 1
    • CTDS1_HUMAN
    • CTDSP1
    • NIF3
    • NLI IF
    • NLI interacting factor 3
    • NLI-IF
    • NLI-interacting factor 3
    • NLIIF
    • Nuclear LIM interactor interacting factor 3
    • Nuclear LIM interactor-interacting factor 3
    • SCP1
    • Small C-terminal domain phosphatase 1
    • Small CTD phosphatase 1
    see all
  • 功能Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residues repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells.
  • 组织特异性Expression is restricted to non-neuronal tissues. Highest expression in skeletal muscle, spleen, lung and placenta.
  • 序列相似性Contains 1 FCP1 homology domain.
  • 细胞定位Nucleus. Colocalizes with RNA polymerase II.
  • Information by UniProt

Recombinant Human CTDSP1 protein (ab124856)参考文献

ab124856 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab124856.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"