- 产品名称Recombinant人CSK protein
参阅全部 CSK 蛋白酶
- 蛋白长度Full length protein
- 来源Escherichia coli
- 分子量50 kDa
- 氨基酸1 to 450
- 标签His tag N-Terminus
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
Constituents: 20% Glycerol, 20mM Tris Cl, 100mM Potassium chloride, 1mM DTT, 0.2mM EDTA, pH 8.0
- C SRC
- C SRC kinase
- C src Tyrosine Kinase
- 功能Specifically phosphorylates 'Tyr-504' on LCK, which acts as a negative regulatory site. Can also act on the LYN and FYN kinases.
- 组织特异性Expressed in lung and macrophages.
- 序列相似性Belongs to the protein kinase superfamily. Tyr protein kinase family. CSK subfamily.
Contains 1 protein kinase domain.
Contains 1 SH2 domain.
Contains 1 SH3 domain.
- 翻译后修饰Autophosphorylation of Tyr-304 occurs only at abnormally high CSK concentrations in vitro.
- 细胞定位Cytoplasm. Cell membrane. Mainly cytoplasmic, also present in lipid rafts.
Information by UniProt
Recombinant Human CSK protein (ab82187)参考文献
has not yet been referenced specifically in any publications.
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