Recombinant人CRCP protein (ab111636)

概述

  • 产品名称Recombinant人CRCP protein
  • 蛋白长度Full length protein

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • AccessionO75575
    • 种属Human
    • 序列MGSSHHHHHHSSGLVPRGSHMEVKDANSALLSNYEVFQLLTDLKEQRKES GKNKHSSGQQNLNTITYETLKYISKTPCRHQSPEIVREFLTALKSHKLTK AEKLQLLNHRPVTAVEIQLMVEESEERLTEEQIEALLHTVTSILPAEPEA EQKKNTNSNVAMDEEDPA
    • 分子量19 kDa including tags
    • 氨基酸1 to 148
    • 标签His tag N-Terminus

技术指标

Our Abpromise guarantee covers the use of ab111636 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Mass Spectrometry

    SDS-PAGE

  • 质谱法
    MALDI-TOF
  • 纯度> 95 % SDS-PAGE.
    qb111636 was purified using conventional chromatography techniques.
  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.32% Tris HCl, 20% Glycerol, 0.02% DTT, 0.58% Sodium chloride

常规信息

  • 别名
    • Calcitonin gene related peptide receptor component
    • Calcitonin gene related peptide receptor component protein
    • Calcitonin gene-related peptide-receptor component protein
    • CGRP receptor component protein
    • CGRP-RCP
    • CGRP-receptor component protein
    • CGRPRCP
    • CRCP
    • DNA-directed RNA polymerase III subunit RPC9
    • HsC17
    • RCP
    • RCP9
    • RNA polymerase III subunit C9
    • RPC9_HUMAN
    see all
  • 功能DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts induce type I interferon and NF- Kappa-B through the RIG-I pathway.
    Accessory protein for the calcitonin gene-related peptide (CGRP) receptor. It modulates CGRP responsiveness in a variety of tissues.
  • 组织特异性Ubiquitous. Most prevalent in testis.
  • 序列相似性Belongs to the eukaryotic RPC9 RNA polymerase subunit family.
  • 细胞定位Nucleus. Cell membrane.
  • Information by UniProt

Recombinant Human CRCP protein 图像

  • 15% SDS-PAGE showing ab111636 at approximately 19.0kDa (3µg).

Recombinant Human CRCP protein (ab111636)参考文献

ab111636 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"