- 来源Escherichia coli
- 序列MGSSHHHHHH SSGLVPRGSH MEFVMKQALG GATKDMGKML GGDEEKDPDA AKKEEERQEA LRQAEEERKA KYAKMEAERE AVRQGIRDKY GIKKKEEREA EAQAAMEANS EGSLTRPKKA IPPGCGDEVE EEDESILDTV IKYLPGPLQD MLKK
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
- 纯度> 90
ab79148 is purified using conventional chromatography techniques.
Endotoxin Level: < 1.0 EU per 1 µg of protein (determined by LAL method)
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Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Constituents: 10% Glycerol, 20mM Tris HCl buffer, pH 8.0
- complexin 1
- Complexin I
- 功能Positively regulates a late step in synaptic vesicle exocytosis. Also involved in glucose-induced secretion of insulin by pancreatic beta-cells.
- 组织特异性Nervous system. In hippocampus and cerebellum, expressed mainly by inhibitory neurons. Overexpressed in substantia nigra from patients with Parkinson disease.
- 序列相似性Belongs to the complexin/synaphin family.
- 细胞定位Cytoplasm > cytosol. Enriched at synaptic-releasing sites in mature neurons.
Information by UniProt
Recombinant Human CPLX1 protein 图像
Recombinant Human CPLX1 protein (ab79148)参考文献
has not yet been referenced specifically in any publications.
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