- 来源Escherichia coli
- 序列MGSSHHHHHHSSGLVPRGSHMEFVMKQALGGATKDMGKMLGGDEEKDPDA AKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEEREA EAQAAMEANSEGSLTRPKKAIPPGCGDEVEEEDESILDTVIKYLPGPLQD MLKK
- 分子量17 kDa including tags
- 氨基酸1 to 134
- 标签His tag N-Terminus
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
- 纯度> 90
ab116466 is sterile filtered
- 补充说明ab116466 is stable 4°C for 4 weeks, should be stored desiccated below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
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Shipped at 4°C. Please see notes section.
Constituents: 0.32% Tris HCl, 10% Glycerol
- complexin 1
- Complexin I
- 功能Positively regulates a late step in synaptic vesicle exocytosis. Also involved in glucose-induced secretion of insulin by pancreatic beta-cells.
- 组织特异性Nervous system. In hippocampus and cerebellum, expressed mainly by inhibitory neurons. Overexpressed in substantia nigra from patients with Parkinson disease.
- 序列相似性Belongs to the complexin/synaphin family.
- 细胞定位Cytoplasm > cytosol. Enriched at synaptic-releasing sites in mature neurons.
Information by UniProt
Recombinant Human CPLX1 protein (ab116466)参考文献
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"