Recombinant人COL4A3BP protein (ab95897)

概述

  • 产品名称
    Recombinant人COL4A3BP protein
  • 蛋白长度
    Protein fragment

描述

  • 性质
    Recombinant
  • 来源
    Escherichia coli
  • 氨基酸序列
    • Accession
    • 种属
      Human
    • 序列
      MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWAGSMLH WPTSLPSGDA FSSVGTHRFV QKVEEMVQNH MTYSLQDVGG DANWQLVVEE GEMKVYRREV EENGIVLDPL KATHAVKGVT GHEVCNYFWN VDVRNDWETT IENFHVVETL ADNAIIIYQT HKRVWPASQR DVLYLSVIRK IPALTENDPE TWIVCNFSVD HDSAPLNNRC VRAKINVAMI CQTLVSPPEG NQEISRDNIL CKITYVANVN PGGWAPASVL RAVAKREYPK FLKRFTSYVQ EKTAGKPILF
    • 分子量
      33 kDa including tags
    • 氨基酸
      347 to 598
    • 标签
      His tag N-Terminus

技术指标

Our Abpromise guarantee covers the use of ab95897 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

    Mass Spectrometry

  • 质谱法
    MALDI-TOF-TOF
  • 纯度
    > 95 % SDS-PAGE.
    ab95897 is purified using conventional chromatography techniques.
  • 形式
    Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Preservative: None
    Constituents: 10% Glycerol, 0.1M Sodium chloride, 20mM Tris HCl, pH 8.0

常规信息

  • 别名
    • Alpha 3 type IV collagen binding protein
    • C43BP_HUMAN
    • Ceramide transfer protein
    • Ceramide transporter
    • CERT
    • Cert protein
    • CERTL
    • col4a3bp
    • Collagen type IV alpha 3 (Goodpasture antigen) binding protein
    • Collagen type IV alpha 3 binding protein
    • Collagen type IV alpha-3-binding protein
    • FLJ20597
    • Goodpasture antigen binding protein
    • Goodpasture antigen-binding protein
    • GPBP
    • hCERT
    • Lipid transfer protein CERTL
    • Procollagen type IV alpha 3 (Goodpasture antigen) binding protein
    • StAR related lipid transfer (START) domain containing 11
    • StAR related lipid transfer protein 11
    • StAR-related lipid transfer protein 11
    • StARD 11
    • StARD11
    • START domain containing 11
    • START domain containing protein 11
    • START domain-containing protein 11
    see all
  • 功能
    May mediate the intracellular trafficking of ceramide in a non-vesicular manner.
  • 组织特异性
    Widely expressed.
  • 序列相似性
    Contains 1 PH domain.
    Contains 1 START domain.
  • 结构域
    The START domain recognizes ceramide and mediates the intermembrane transfer of ceramide.
    The PH domain targets the Golgi apparatus.
    The FFAT motif is required for interaction with VAPA and VAPB.
  • 翻译后修饰
    Phosphorylation on Ser-132 decreases the affinity toward phosphatidylinositol 4-phosphate at Golgi membranes and reduces ceramide transfer activity.
  • 细胞定位
    Cytoplasm. Golgi apparatus. Endoplasmic reticulum. Preferentially localized to the Golgi apparatus.
  • Information by UniProt

图片

  • 15% SDS-PAGE showing ab95897 at approximately 33.1kDa (3µg).

文献

This product has been referenced in:
  • Fleury L  et al. Development of a CERT START Domain-Ceramide HTRF Binding Assay and Application to Pharmacological Studies and Screening. J Biomol Screen 20:779-87 (2015). Read more (PubMed: 25716975) »

See 1 Publication for this product

客户评价及客户问答

Nous n'avons pas essayé cette protéine dans un tampon PBS donc nous ne savons pas si cette protéine devient instable dans ce tampon. Cependant, le laboratoire nous a dit qu’il est recommandé de garder le glycerol dans ...

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Merci de nous avoir contactés.

Nous n'avons pas mesuré le coefficient d'absorption molaire exact à 280 nm, mais voici quelques informations à propos de la valeur théorique.

Selon l'outil ProtParam ...

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Merci de nous avoir contactés.

Nous avons deux protéines au catalogue avec ce nom : ab40265 et ab95897. Pourriez-vous me dire pour laquelle de ces références vous souhaitez connaître le coefficient d'absorpti...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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