Recombinant人Cofilin protein (ab85154)

概述

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • 种属Human

技术指标

Our Abpromise guarantee covers the use of ab85154 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

    Western blot

  • 形式Liquid
  • 补充说明

    ab85154 (Human Cofilin full length protein) can be utilized as a substrate for the following active protein kinases:

     

    ab140418 (Active human TESK2 full length protein)

    ab174066 (Active human LIMK1 protein fragment)

  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: 150mM Imidazole
    Constituents: 25% Glycerol, 50mM Sodium phosphate, 300mM Sodium chloride, 2mM DTT, 0.1mM PMSF, pH 7.0

常规信息

  • 别名
    • 18 kDa phosphoprotein
    • CFL
    • CFL 1
    • CFL1
    • COF1_HUMAN
    • Cofilin
    • Cofilin 1
    • Cofilin 1 non muscle
    • Cofilin non muscle isoform
    • Cofilin-1
    • epididymis secretory protein Li 15
    • HEL-S-15
    • non-muscle isoform
    • p18
    see all
  • 功能Controls reversibly actin polymerization and depolymerization in a pH-sensitive manner. It has the ability to bind G- and F-actin in a 1:1 ratio of cofilin to actin. It is the major component of intranuclear and cytoplasmic actin rods.
  • 组织特异性Widely distributed in various tissues.
  • 序列相似性Belongs to the actin-binding proteins ADF family.
    Contains 1 ADF-H domain.
  • 翻译后修饰Phosphorylated on Ser-3 in resting cells.
  • 细胞定位Nucleus matrix. Cytoplasm > cytoskeleton. Almost completely in nucleus in cells exposed to heat shock or 10% dimethyl sulfoxide.
  • Information by UniProt

Recombinant Human Cofilin protein 图像

  • SDS-PAGE showing ab85154 at approximately 23kDa.

Recombinant Human Cofilin protein (ab85154)参考文献

ab85154 has not yet been referenced specifically in any publications.

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