Recombinant人CINP protein (ab109973)

概述

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • AccessionQ9BW66
    • 种属Human
    • 序列MGSSHHHHHHSSGLVPRGSHMEAKTLGTVTPRKPVLSVSARKIKDNAADW HNLILKWETLNDAGFTTANNIANLKISLLNKDKIELDSSSPASKENEEKV CLEYNEELEKLCEELQATLDGLTKIQVKMEKLSSTTKGICELENYHYGEE SKRPPLFHTWPTTHFYEVSHKLLEMYRKELLLKRTVAKELAHTGDPDLTL SYLSMWLHQPYVESDSRLHLESMLLETGHRAL
    • 分子量26 kDa including tags
    • 氨基酸1 to 212
    • 标签His tag N-Terminus

技术指标

Our Abpromise guarantee covers the use of ab109973 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

    Mass Spectrometry

  • 质谱法
    MALDI-TOF
  • 纯度> 95 % SDS-PAGE.
    ab109973 was purified using conventional chromatography.
  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    Preservative: None
    Constituents: 20% Glycerol, 0.1M Sodium chloride, 20mM Tris HCl, 1mM DTT, pH 8.0

常规信息

  • 别名
    • CDK2-interacting protein
    • CINP
    • CINP protein
    • CINP_HUMAN
    • Cyclin dependent kinase 2 interacting protein
    • Cyclin-dependent kinase 2-interacting protein
    • MGC849
    see all
  • 功能Interacts with the components of the replication complex and 2 kinases, CDK2 and CDC7, thereby providing a functional and physical link between CDK2 and CDC7 during firing of the origins of replication. Regulates ATR-mediated checkpoint signaling.
  • 序列相似性Belongs to the CINP family.
  • 翻译后修饰Phosphorylated by CDC7 but not by CDK2.
  • 细胞定位Nucleus. Binds to nuclear under G1 conditions, and dissociates from chromatin with the start of DNA replication.
  • Information by UniProt

Recombinant Human CINP protein 图像

  • 15% SDS-PAGE analysis of 3 µg ab109973.

Recombinant Human CINP protein (ab109973)参考文献

ab109973 has not yet been referenced specifically in any publications.

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