产品名称 Recombinant人CINP protein
蛋白长度 Full length protein 描述
来源 Escherichia coli
序列 MGSSHHHHHHSSGLVPRGSHMEAKTLGTVTPRKPVLSVSARKIKDNAADW HNLILKWETLNDAGFTTANNIANLKISLLNKDKIELDSSSPASKENEEKV CLEYNEELEKLCEELQATLDGLTKIQVKMEKLSSTTKGICELENYHYGEE SKRPPLFHTWPTTHFYEVSHKLLEMYRKELLLKRTVAKELAHTGDPDLTL SYLSMWLHQPYVESDSRLHLESMLLETGHRAL
分子量 26 kDa including tags
氨基酸 1 to 212
标签 His tag N-Terminus 技术指标
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
纯度 > 95
% SDS-PAGE. ab109973 was purified using conventional chromatography.
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Constituents: 20% Glycerol, 0.1M Sodium chloride, 20mM Tris HCl, 1mM DTT, pH 8.0
功能 Interacts with the components of the replication complex and 2 kinases, CDK2 and CDC7, thereby providing a functional and physical link between CDK2 and CDC7 during firing of the origins of replication. Regulates ATR-mediated checkpoint signaling.
序列相似性 Belongs to the CINP family.
翻译后修饰 Phosphorylated by CDC7 but not by CDK2.
细胞定位 Nucleus. Binds to nuclear under G1 conditions, and dissociates from chromatin with the start of DNA replication.
Information by UniProt
Recombinant Human CINP protein 图像
Recombinant Human CINP protein (ab109973)参考文献
has not yet been referenced specifically in any publications.
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