Recombinant人cIAP2 protein (ab112252)

概述

描述

  • 性质Recombinant
  • 来源Wheat germ
  • 氨基酸序列
    • AccessionQ13489
    • 种属Human
    • 序列MNIVENSIFLSNLMKSANTFELKYDLSCELYRMSTYSTFPAGVPVSERSL ARAGFYYTGVNDKVKCFCCGLMLDNWKRGDSPTEKHKKLYPSCRFVQSLN SVNNLEATSQPTFPSSVTNSTHSLLPGTENSGYFRGSYSNSPSNPVNSRA NQDFSALMRSSYHCAMNNENARLLTFQTWPLTFLSPTDLAKAGFYYIGPG DRVACFACGGKLSNWEPKDNAMSEHLRHFPKCPFIENQLQDTSRYTVSNL SMQTH
    • 分子量95 kDa including tags
    • 氨基酸1 to 604
    • 标签GST tag N-Terminus

技术指标

Our Abpromise guarantee covers the use of ab112252 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Western blot

    SDS-PAGE

    ELISA

  • 形式Liquid
  • 补充说明Best use within three months from the date of receipt of this protein.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl
    Note: Glutathione is reduced

常规信息

  • 别名
    • AIP 1
    • AIP1
    • API 2
    • API2
    • Apoptosis inhibitor 2
    • Baculoviral IAP repeat containing 3
    • Baculoviral IAP repeat containing protein 3
    • Baculoviral IAP repeat-containing protein 3
    • BIRC 3
    • BIRC3
    • BIRC3_HUMAN
    • C IAP2
    • C-IAP2
    • CIAP 2
    • CIAP2
    • HAIP 1
    • HAIP1
    • HIAP 1
    • HIAP-1
    • HIAP1
    • IAP homolog C
    • IAP-1
    • Inhibitor of apoptosis protein 1
    • MALT 2
    • MALT2
    • Mammalian IAP homolog C
    • MIHC
    • RING finger protein 49
    • RNF49
    • TNFR2 TRAF signaling complex protein 1
    • TNFR2 TRAF signalling complex protein
    • TNFR2-TRAF-signaling complex protein 1
    see all
  • 功能Apoptotic suppressor. The BIR motifs region interacts with TNF receptor associated factors 1 and 2 (TRAF1 and TRAF2) to form an heteromeric complex, which is then recruited to the tumor necrosis factor receptor 2 (TNFR2).
  • 组织特异性Highly expressed in fetal lung, and kidney. In the adult, expression is mainly seen in lymphoid tissues, including spleen, thymus and peripheral blood lymphocytes.
  • 疾病相关Note=A chromosomal aberration involving BIRC3 is recurrent in low-grade mucosa-associated lymphoid tissue (MALT lymphoma). Translocation t(11;18)(q21;q21) with MALT1. This translocation is found in approximately 50% of cytogenetically abnormal low-grade MALT lymphoma.
  • 序列相似性Belongs to the IAP family.
    Contains 3 BIR repeats.
    Contains 1 CARD domain.
    Contains 1 RING-type zinc finger.
  • 细胞定位Cytoplasm.
  • Information by UniProt

Recombinant Human cIAP2 protein 图像

  • Coomassie blue stained 12.5% SDS page analysis of ab112252

Recombinant Human cIAP2 protein (ab112252)参考文献

ab112252 has not yet been referenced specifically in any publications.

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