Recombinant人CENPH protein (denatured) (ab113134)

概述

  • 产品名称Recombinant人CENPH protein (denatured)
    参阅全部 CENPH 蛋白酶
  • 蛋白长度Protein fragment
  • 描述
    Recombinant人CENPH protein

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • AccessionQ9H3R5
    • 种属Human
    • 序列MGSSHHHHHHSSGLVPRGSHMLNKLIMKSQQESWDLEEKLLDI RKKRL QLKQASESKLLEIQTEKNKQKIDLDSMENSERIKIIRQNLQMEIK ITT VIQHVFQNLILGSKVNWAEDPALKEIVLQLEKNVDMM
    • 分子量16 kDa including tags
    • 氨基酸136 to 247
    • 标签His tag N-Terminus

技术指标

Our Abpromise guarantee covers the use of ab113134 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

  • 纯度> 90 % SDS-PAGE.
    ab113134 was denatured using detergent during a conventional chromatography purification process.
  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 0.32% Tris HCl, 10% Glycerol

常规信息

  • 别名
    • CENP H
    • CENP-H
    • CENPH
    • CENPH_HUMAN
    • Centromere protein H
    • ICEN35
    • Interphase centromere complex protein 35
    • Kinetochore protein CENP H
    • NNF1
    • NNF1, MIND kinetochore complex component, homolog
    • PMF1
    see all
  • 功能Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres. Required for chromosome congression and efficiently align the chromosomes on a metaphase plate.
  • 序列相似性Belongs to the centromere protein H family.
  • 细胞定位Nucleus. Chromosome > centromere > kinetochore. Associates with active centromere-kinetochore complexes throughout the cell cycle. Colocalizes with inner kinetochore plate proteins CENPA and CENPC1 during both interphase and metaphase.
  • Information by UniProt

Recombinant Human CENPH protein (denatured) 图像

  • 15% SDS-PAGE analysis of 3 µg ab113134.

Recombinant Human CENPH protein (denatured) (ab113134)参考文献

ab113134 has not yet been referenced specifically in any publications.

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