Recombinant人CDK1 protein (ab64306)

概述

描述

  • 性质Recombinant
  • 来源Baculovirus infected Sf9 cells
  • 氨基酸序列
    • AccessionP06493
    • 种属Human
    • 序列MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIR EISLLKELRH PNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQ YMDSSLVKSYLYQILQGIVFCH SRRVLHRDLKPQNLLIDDKGTIKLAD FGLARAFGIPIRVYTHEVVTLWYRSPEVLLGSAR YSTPVDIWSIGTIF AELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNT FP KWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFNDLDN QIKKM
    • 氨基酸1 to 297
    • 标签GST tag N-Terminus

技术指标

Our Abpromise guarantee covers the use of ab64306 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

  • 形式Liquid
  • 补充说明This protein is inactive. CDK1 is activated by its counterpart Cyclin (eg. Cyclin A). Since CDK1 is not expressed with Cyclin, the protein is inactive
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 25% Glycerol, 50mM Sodium chloride, 50mM Tris HCl, 0.25mM DTT, 0.1mM EDTA, 0.1mM PMSF, pH 7.5

常规信息

  • 别名
    • Cdc 2
    • Cdc2
    • CDC28A
    • CDK 1
    • CDK1
    • CDK1_HUMAN
    • CDKN1
    • CELL CYCLE CONTROLLER CDC2
    • Cell division control protein 2
    • Cell division control protein 2 homolog
    • Cell division cycle 2 G1 to S and G2 to M
    • Cell division protein kinase 1
    • Cell Divsion Cycle 2 Protein
    • Cyclin Dependent Kinase 1
    • Cyclin-dependent kinase 1
    • DKFZp686L20222
    • MGC111195
    • p34 Cdk1
    • p34 protein kinase
    • P34CDC2
    see all
  • 功能Plays a key role in the control of the eukaryotic cell cycle. It is required in higher cells for entry into S-phase and mitosis. p34 is a component of the kinase complex that phosphorylates the repetitive C-terminus of RNA polymerase II.
  • 组织特异性Isoform 2 is found in breast cancer tissues.
  • 序列相似性Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
    Contains 1 protein kinase domain.
  • 细胞定位Nucleus.
  • Information by UniProt

Recombinant Human CDK1 protein 图像

  • ab64306 on SDS-PAGE, MW 58kDa.

Recombinant Human CDK1 protein (ab64306)参考文献

ab64306 has not yet been referenced specifically in any publications.

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