Recombinant人CD97 protein (ab114866)

概述

描述

  • 性质Recombinant
  • 来源Wheat germ
  • 氨基酸序列
    • AccessionP48960
    • 种属Human
    • 序列KKQAELEEIYESSIRGVQLRRLSAVNSIFLSHNNTKELNSPILFAFSHLE SSDGEAGRDPPAKDVMPGPRQELLCAFWKSDSDRGGHWATEGCQVLGSKN GSTTCQCSH
    • 分子量38 kDa including tags
    • 氨基酸421 to 529

技术指标

Our Abpromise guarantee covers the use of ab114866 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    ELISA

    SDS-PAGE

    Western blot

  • 形式Liquid
  • 补充说明Protein concentration is above or equal to 0.05 mg/ml.
    This protein is best used within three months from the date of receipt.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

常规信息

  • 别名
    • ADGRE5
    • Adhesion G protein-coupled receptor E5
    • CD 97
    • CD_antigen=CD97
    • CD97
    • CD97 antigen
    • CD97 antigen subunit beta
    • CD97 molecule
    • CD97_HUMAN
    • Leukocyte antigen CD97
    • Seven span transmembrane protein
    • Seven transmembrane helix receptor
    • Seven transmembrane heterodimeric receptor associated with inflammation
    • TM7LN 1
    • TM7LN1
    see all
  • 功能Receptor potentially involved in both adhesion and signaling processes early after leukocyte activation. Plays an essential role in leukocyte migration.
  • 组织特异性Broadly expressed, found on most hematopoietic cells, including activated lymphocytes, monocytes, macrophages, dendritic cells, and granulocytes. Expressed also abundantly by smooth muscle cells. Expressed in thyroid, colorectal, gastric, esophageal and pancreatic carcinomas too. Expression are increased under inflammatory conditions in the CNS of multiple sclerosis and in synovial tissue of patients with rheumatoid arthritis. Increased expression of CD97 in the synovium is accompagnied by detectable levels of soluble CD97 in the synovial fluid.
  • 序列相似性Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.
    Contains 5 EGF-like domains.
    Contains 1 GPS domain.
  • 结构域The first two EGF domains mediate the interaction with DAF. A third tandemly arranged EGF domain is necessary for the structural integrity of the binding region.
    Binding to chondroitin sulfate is mediated by the fourth EGF domain.
  • 翻译后修饰Proteolytically cleaved into 2 subunits, an extracellular alpha subunit and a seven-transmembrane subunit.
  • 细胞定位Cell membrane and Secreted > extracellular space.
  • Information by UniProt

Recombinant Human CD97 protein 图像

  • ab114866 analysed by 12.5% SDS-PAGE and stained with Coomassie Blue.

Recombinant Human CD97 protein (ab114866)参考文献

ab114866 has not yet been referenced specifically in any publications.

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