产品名称 Recombinant人CD86 protein 参阅全部 CD86 蛋白酶
蛋白长度 Full length protein 描述
来源 Wheat germ
序列 MDPQCTMGLSNILFVMAFLLSGAAPLKIQAYFNETADLPCQFANSQNQSL SELVVFWQDQENLVLNEVYLGKEKF
DSVHSKYMGRTSFDSDSWTLRLH NLQIKDKGLYQCIIHHKKPTGMIRIHQMNSELSVLANFSQPEIVPISNIT EN
RLLSSPFSIELEDPQPPPD HIPWITAVLPTVIICVMVFCLILWKWKKKKRPRNSYKCGTNTMEREESEQ TKKREK
分子量 62 kDa including tags
氨基酸 1 to 329 技术指标
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
补充说明 Protein concentration is above or equal to 0.05 mg/ml
Concentration information loading... 制备和贮存
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
Constituents: 0.3% Glutathione, 0.79% Tris HCl
Activation B7-2 antigen
Activation B7-2 antigen 3
B-lymphocyte activation antigen B7-2
功能 Receptor involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. May play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation. Isoform 2 interferes with the formation of CD86 clusters, and thus acts as a negative regulator of T-cell activation.
组织特异性 Expressed by activated B-lymphocytes and monocytes.
序列相似性 Contains 1 Ig-like C2-type (immunoglobulin-like) domain. Contains 1 Ig-like V-type (immunoglobulin-like) domain.
翻译后修饰 Polyubiquitinated; which is promoted by MARCH8 and results in endocytosis and lysosomal degradation.
Information by UniProt
Recombinant Human CD86 protein 图像
Recombinant Human CD86 protein (ab114228)参考文献
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"