Recombinant人CD8 beta protein (ab112264)

概述

描述

  • 性质
    Recombinant
  • 来源
    Wheat germ
  • 氨基酸序列
    • Accession
    • 种属
      Human
    • 序列
      MRPRLWLLLAAQLTVLHGNSVLQQTPAYIKVQTNKMVMLSCEAKISLSNM RIYWLRQRQAPSSDSHHEFLALWDSAKGTIHGEEVEQEKIAVFRDASRFI LNLTSVKPEDSGIYFCMIVGSPELTFGKGTQLSVVDFLPTTAQPTKKSTL KKRVCRLPRPETQKGPLCSPITLGLLVAGVLVLLVSLGVAIHLCCRRRRA RLRFMKQPQGEGISGTFVPQCLHGYYSNTTTSQKLLNPWILKT
    • 分子量
      53 kDa including tags
    • 氨基酸
      1 to 243
    • 标签
      GST tag N-Terminus

技术指标

Our Abpromise guarantee covers the use of ab112264 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Western blot

    ELISA

    SDS-PAGE

  • 形式
    Liquid
  • 补充说明
    Best use within three months from the date of receipt of this protein.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.79% Tris HCl, 0.31% Glutathione

常规信息

  • 别名
    • CD8b antigen
    • CD8 antigen beta polypeptide 1
    • CD8 antigen beta polypeptide 1 (p37)
    • CD8 beta
    • CD8b
    • CD8b molecule
    • CD8B_HUMAN
    • CD8B1
    • Leu2
    • Ly3
    • LYT3
    • MGC119115
    • P37
    • T cell surface glycoprotein CD8 beta chain
    • T lymphocyte surface glycoprotein beta chain
    • T-cell surface glycoprotein CD8 beta chain
    see all
  • 功能
    Identifies cytotoxic/suppressor T-cells that interact with MHC class I bearing targets. CD8 is thought to play a role in the process of T-cell mediated killing.
  • 组织特异性
    Isoform 1, isoform 3, isoform 5, isoform 6, isoform 7 and isoform 8 are expressed in both thymus and peripheral CD8+ T-cells. Expression of isoform 1 is higher in thymus CD8+ T-cells than in peripheral CD8+ T-cells. Expression of isoform 6 is higher in peripheral CD8+ T-cells than in thymus CD8+ T-cells.
  • 序列相似性
    Contains 1 Ig-like V-type (immunoglobulin-like) domain.
  • 翻译后修饰
    Phosphorylated as a consequence of T-cell activation.
  • 细胞定位
    Secreted and Cell membrane.
  • Information by UniProt

图片

  • ab112264 on a 12.5% SDS-PAGE Stained with Coomassie Blue.

文献

ab112264 has not yet been referenced specifically in any publications.

客户评价及客户问答

Thank you for calling Abcam on Friday. For CD4, I have found the following set Protein: ab111463, fragment from 29-390. Antibodies: ab67480, aa7****                      ab51312, aa******* I know that the antibodies bind very close to each other, but t...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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