Recombinant人CD8 alpha protein (ab114161)

概述

描述

  • 性质Recombinant
  • 来源Wheat germ
  • 氨基酸序列
    • AccessionP01732
    • 种属Human
    • 序列SQFRVSPLDRTWNLGETVELKCQVLLSNPTSGCSWLFQPRGAAASPTFLL YLSQNKPKAAEGLDTQRFSGKRLGDTFVLTLSDFRRENEGYYFCSALSNS IMYFSHFVPV
    • 分子量38 kDa including tags
    • 氨基酸22 to 131
    • 标签GST tag N-Terminus

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技术指标

Our Abpromise guarantee covers the use of ab114161 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Western blot

    ELISA

    SDS-PAGE

  • 形式Liquid
  • 补充说明Protein concentration is above or equal to 0.05 mg/ml.
    ab114161 is best used within three months from the date of receipt.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

常规信息

  • 别名
    • alpha polypeptide (p32)
    • CD8
    • CD8 antigen alpha polypeptide
    • CD8 antigen alpha polypeptide (p32)
    • CD8a
    • CD8A antigen
    • CD8A molecule
    • CD8A_HUMAN
    • Leu2
    • Leu2 T lymphocyte antigen
    • Ly3
    • LYT3
    • MAL
    • OKT8 T cell antigen
    • OTTHUMP00000160760
    • OTTHUMP00000160764
    • OTTHUMP00000203528
    • OTTHUMP00000203721
    • p32
    • T cell antigen Leu2
    • T cell co receptor
    • T-cell surface glycoprotein CD8 alpha chain
    • T-lymphocyte differentiation antigen T8/Leu-2
    • T8 T cell antigen
    • T8/Leu-2 T-lymphocyte differentiation antigen
    see all
  • 功能Identifies cytotoxic/suppressor T-cells that interact with MHC class I bearing targets. CD8 is thought to play a role in the process of T-cell mediated killing. CD8 alpha chains binds to class I MHC molecules alpha-3 domains.
  • 疾病相关Defects in CD8A are a cause of familial CD8 deficiency (CD8 deficiency) [MIM:608957]. Familial CD8 deficiency is a novel autosomal recessive immunologic defect characterized by absence of CD8+ cells, leading to recurrent bacterial infections.
  • 序列相似性Contains 1 Ig-like V-type (immunoglobulin-like) domain.
  • 翻译后修饰All of the five most carboxyl-terminal cysteines form inter-chain disulfide bonds in dimers and higher multimers, while the four N-terminal cysteines do not.
  • 细胞定位Secreted and Cell membrane.
  • Information by UniProt

Recombinant Human CD8 alpha protein 图像

  • 12.5% SDS-PAGE analysis of ab114161, stained with Coomassie Blue.

Recombinant Human CD8 alpha protein (ab114161)参考文献

ab114161 has not yet been referenced specifically in any publications.

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