Recombinant人CD55 protein (ab80038)

概述

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • 种属Human
    • 序列LPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQW SDIEEFCNR
    • 氨基酸38 to 96

技术指标

Our Abpromise guarantee covers the use of ab80038 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Western blot

    ELISA

    SDS-PAGE

  • 纯度> 90 % SDS-PAGE.

  • 形式Lyophilised
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: PBS

  • 复溶Redissolve the powder with 1ml sterile water will restore to the original concentration 1mg/ml.

常规信息

  • 别名
    • CD 55
    • CD55
    • CD55 antigen
    • CD55 Cromer blood group system
    • CD55 molecule
    • CD55 molecule, decay accelerating factor for complement (Cromer blood group)
    • Cd55a
    • Complement decay accelerating factor
    • Complement decay-accelerating factor
    • Complement decay-accelerating factor, GPI-anchored
    • CR
    • CROM
    • Cromer Blood Group antigen
    • Cromer blood group system
    • DAF
    • Daf-GPI
    • DAF_HUMAN
    • Daf1
    • Dcay accelerating factor for complement (CD55, Cromer blood group system)
    • Decay accelarating factor 1, isoform CRA_a
    • Decay accelerating factor (GPI-form)
    • Decay Accelerating Factor for Complement
    • Decay accelerating factor GPI-form
    • Decay accelerating factor soluble-form
    • GPI-DAF
    • TC
    see all
  • 功能This protein recognizes C4b and C3b fragments that condense with cell-surface hydroxyl or amino groups when nascent C4b and C3b are locally generated during C4 and c3 activation. Interaction of daf with cell-associated C4b and C3b polypeptides interferes with their ability to catalyze the conversion of C2 and factor B to enzymatically active C2a and Bb and thereby prevents the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade.
  • 组织特异性Expressed on the plasma membranes of all cell types that are in intimate contact with plasma complement proteins. It is also found on the surfaces of epithelial cells lining extracellular compartments, and variants of the molecule are present in body fluids and in extracellular matrix.
  • 序列相似性Belongs to the receptors of complement activation (RCA) family.
    Contains 4 Sushi (CCP/SCR) domains.
  • 结构域The first Sushi domain (SCR1) is not necessary for function. SCR2 and SCR4 provide the proper conformation for the active site on SCR3.
  • 翻译后修饰The Ser/Thr-rich domain is heavily O-glycosylated.
  • 细胞定位Cell membrane.
  • Information by UniProt

Recombinant Human CD55 protein 图像

  • 20% SDS PAGE gel, Commassie blue staining.

Recombinant Human CD55 protein (ab80038)参考文献

ab80038 has not yet been referenced specifically in any publications.

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