Recombinant人CD42a protein (ab114525)

概述

描述

  • 性质Recombinant
  • 来源Wheat germ
  • 氨基酸序列
    • AccessionP14770
    • 种属Human
    • 序列MPAWGALFLLWATAEATKDCPSPCTCRALETMGLWVDCRGHGLTALPALP ARTRHLLLANNSLQSVPPGAFDHLPQLQTLDVTQNPWHCDCSLTYLRLWL EDRTPEALLQVRCASPSLAAHGPLGRLTGYQLGSCGWQLQASWVRPGVLW DVALVTVAALGLALLAGLLCATTEALD
    • 分子量46 kDa including tags
    • 氨基酸1 to 177

技术指标

Our Abpromise guarantee covers the use of ab114525 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    ELISA

    SDS-PAGE

    Western blot

  • 形式Liquid
  • 补充说明Protein concentration is above or equal to 0.05 µg/ul. Best use within three months from the date of receipt of this protein.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

常规信息

  • 别名
    • CD42a
    • Glycoprotein 9
    • Glycoprotein IX
    • Glycoprotein IX (platelet)
    • Glycoprotein IX precursor
    • GP IX
    • GP-IX
    • GP9
    • GPIX
    • GPIX_HUMAN
    • Platelet glycoprotein IX
    see all
  • 功能The GPIb-V-IX complex functions as the vWF receptor and mediates vWF-dependent platelet adhesion to blood vessels. The adhesion of platelets to injured vascular surfaces in the arterial circulation is a critical initiating event in hemostasis. GP-IX may provide for membrane insertion and orientation of GP-Ib.
  • 疾病相关Defects in GP9 are a cause of Bernard-Soulier syndrome (BSS) [MIM:231200]; also known as giant platelet disease (GPD). BSS patients have unusually large platelets and have a clinical bleeding tendency.
  • 序列相似性Contains 1 LRR (leucine-rich) repeat.
    Contains 1 LRRCT domain.
    Contains 1 LRRNT domain.
  • 细胞定位Membrane.
  • Information by UniProt

Recombinant Human CD42a protein 图像

  • 12.5% SDS-PAGE showing ab114525 at approximately 45.54kDa stained with Coomassie Blue.

Recombinant Human CD42a protein (ab114525)参考文献

ab114525 has not yet been referenced specifically in any publications.

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