Recombinant人CD3D protein (ab114152)

概述

描述

  • 性质
    Recombinant
  • 来源
    Wheat germ
  • 氨基酸序列
    • Accession
    • 种属
      Human
    • 序列
      MEHSTFLSGLVLATLLSQVSPFKIPIEELEDRVFVNCNTSITWVEGTVGT LLSDITRLDLGKRILDPRGIYRCNGTDIYKDKESTVQVHYRMCQSCVELD PATVAGIIVTDVIATLLLALGVFCFAGHETGRLSGAADTQALLRNDQVYQ PLRDRDDAQYSHLGGNWARNK
    • 分子量
      45 kDa including tags
    • 氨基酸
      1 to 171

技术指标

Our Abpromise guarantee covers the use of ab114152 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    ELISA

    Western blot

    SDS-PAGE

  • 形式
    Liquid
  • 补充说明
    Protein concentration is above or equal to 0.05 mg/ml.
    ab114152 is best used within three months from the date of receipt.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

常规信息

  • 别名
    • CD3 antigen delta subunit
    • CD3 delta
    • CD3-delta
    • CD3d
    • CD3d antigen delta polypeptide (TiT3 complex)
    • CD3d molecule
    • CD3d molecule delta (CD3-TCR complex)
    • CD3D_HUMAN
    • IMD19
    • OKT3 delta chain
    • T cell receptor T3 delta chain
    • T-cell receptor T3 delta chain
    • T-cell surface glycoprotein CD3 delta chain
    • T3D
    see all
  • 功能
    The CD3 complex mediates signal transduction.
  • 疾病相关
    Defects in CD3D are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (T(-)/B(+)/NK(+) SCID) [MIM:608971]. A form of severe combined immunodeficiency (SCID), a genetically and clinically heterogeneous group of rare congenital disorders characterized by impairment of both humoral and cell-mediated immunity, leukopenia, and low or absent antibody levels. Patients present in infancy recurrent, persistent infections by opportunistic organisms. The common characteristic of all types of SCID is absence of T-cell-mediated cellular immunity due to a defect in T-cell development.
  • 序列相似性
    Contains 1 ITAM domain.
  • 细胞定位
    Membrane.
  • Information by UniProt

图片

  • 12.5% SDS-PAGE analysis of ab114152, stained with Coomassie Blue.

文献

ab114152 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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