Recombinant人CD3 zeta protein (ab112263)

概述

描述

  • 性质Recombinant
  • 来源Wheat germ
  • 氨基酸序列
    • AccessionP20963
    • 种属Human
    • 序列MKWKALFTAAILQAQLPITEAQSFGLLDPKLCYLLDGILFIYGVILTALF LRVKFSRSADAPAYQQGQNQLYNELNLGRREEYDVLDKRRGRDPEMGGKP QRRKNPQEGLYNELQKDKMAEAYSEIGMKGERRRGKGHDGLYQGLSTATK DTYDALHMQALPPR
    • 分子量44 kDa including tags
    • 氨基酸1 to 164
    • 标签GST tag N-Terminus

技术指标

Our Abpromise guarantee covers the use of ab112263 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    ELISA

    Western blot

    SDS-PAGE

  • 形式Liquid
  • 补充说明Best use within three months from the date of receipt of this protein.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.79% Tris HCl, 0.31% Glutathione

常规信息

  • 别名
    • 4930549J05Rik
    • A430104F18Rik
    • AW552088
    • CD247
    • CD247 antigen
    • Cd247 molecule
    • Cd3
    • CD3 antigen, zeta polypeptide, isoform CRA_b
    • CD3 antigen, zeta subunit
    • CD3-eta
    • CD3H
    • CD3Q
    • Cd3z
    • CD3Z antigen zeta polypeptide (TiT3 complex)
    • CD3Z_HUMAN
    • CD3zeta
    • CD3zeta chain
    • MGC140430
    • T cell receptor T3 zeta chain
    • T cell surface glycoprotein CD3 zeta chain
    • T-cell antigen receptor complex, zeta subunit of CD3
    • T-cell receptor T3 zeta chain
    • T-cell surface glycoprotein CD3 zeta chain
    • T3z
    • TCR zeta chain
    • TCRk
    • TCRZ
    • TCRzeta
    see all
  • 功能Probable role in assembly and expression of the TCR complex as well as signal transduction upon antigen triggering.
  • 疾病相关Defects in CD247 are the cause of immunodeficiency due to defect in CD3-zeta (CD3ZID) [MIM:610163]. An immunological deficiency characterized by T-cells impaired immune response to alloantigens, tetanus toxoid and mitogens.
  • 序列相似性Belongs to the CD3Z/FCER1G family.
    Contains 3 ITAM domains.
  • 结构域The ITAM domains mediate interaction with SHB.
  • 翻译后修饰Phosphorylated on Tyr residues after T-cell receptor triggering.
  • 细胞定位Membrane.
  • Information by UniProt

Recombinant Human CD3 zeta protein 图像

  • ab112263 on a 12.5% SDS-PAGE Stained with Coomassie Blue.

Recombinant Human CD3 zeta protein (ab112263)参考文献

ab112263 has not yet been referenced specifically in any publications.

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