Recombinant人CCDC5 protein (ab124590)

概述

  • 产品名称Recombinant人CCDC5 protein
  • 蛋白长度Full length protein

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • AccessionQ96CS2
    • 种属Human
    • 序列MGSSHHHHHH SSGLVPRGSH MGSHMEPQEE RETQVAAWLK KIFGDHPIPQ YEVNPRTTEI LHHLSERNRV RDRDVYLVIE DLKQKASEYE SEAKYLQDLL MESVNFSPAN LSSTGSRYLN ALVDSAVALE TKDTSLASFI PAVNDLTSDL FRTKSKSEEI KIELEKLEKN LTATLVLEKC LQEDVKKAEL HLSTERAKVD NRRQNMDFLK AKSEEFRFGI KAAEEQLSAR GMDASLSHQS LVALSEKLAR LKQQTIPLKK KLESYLDLMP NPSLAQVKIE EAKRELDSIE AELTRRVDMM EL
    • 分子量34 kDa including tags
    • 氨基酸1 to 278
    • 标签His tag N-Terminus

技术指标

Our Abpromise guarantee covers the use of ab124590 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

    Mass Spectrometry

  • 质谱法
    MALDI-TOF
  • 纯度> 85 % SDS-PAGE.
    ab124590 is purified using conventional chromatography techniques.
  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.03% DTT, 0.32% Tris HCl, 50% Glycerol, 1.17% Sodium chloride

常规信息

  • 别名
    • Coiled coil domain containing 5 (spindle associated)
    • Coiled coil domain containing protein 5
    • Coiled-coil domain-containing protein 5
    • Enhancer of invasion cluster
    • Enhancer of invasion-cluster
    • HAUS augmin-like complex subunit 1
    • HAUS1
    • HAUS1_HUMAN
    • HEI-C
    • HEIC
    • HsT1461
    see all
  • 功能Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex.
  • 组织特异性Widely expressed. Expressed in pancreas, kidney, skeletal muscle, liver and heart. Weakly expressed in lung, brain and placenta.
  • 序列相似性Belongs to the HAUS1 family.
  • 细胞定位Cytoplasm. Cytoplasm > cytoskeleton > centrosome. Cytoplasm > cytoskeleton > spindle. Cytoplasm > cytoskeleton > spindle pole. Localizes with the spindle poles in mitotic cells. In metaphase, localizes to the mitotic asters and is highly punctate on the microtubule array. During later stages of mitosis, remains on the spindle but is not present at the interzone, and is finally observed at the microtubule bundles proximal to the midbody, clearly excluded from the midbody. In contrast, does not colocalize with the tubulin cytoskeleton in interphase cells. In interphase, localized at the centrosome and diffusely in the cytoplasm.
  • Information by UniProt

Recombinant Human CCDC5 protein 图像

  • 15% SDS-PAGE showing ab124590 (3µg).

Recombinant Human CCDC5 protein (ab124590)参考文献

ab124590 has not yet been referenced specifically in any publications.

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