Human heterochromatin protein p25 mRNA complete cds
Modifier 1 protein
功能Component of heterochromatin. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. Interaction with lamin B receptor (LBR) can contribute to the association of the heterochromatin with the inner nuclear membrane.
组织特异性Expressed in all adult and embryonic tissues.
序列相似性Contains 2 chromo domains.
翻译后修饰Not phosphorylated. Ubiquitinated.
细胞定位Nucleus. Unassociated with chromosomes during mitosis.