Epididymis secretory sperm binding protein Li 130P
HEL S 130P
Lysosomal aspartyl peptidase
Lysosomal aspartyl protease
功能Acid protease active in intracellular protein breakdown. Involved in the pathogenesis of several diseases such as breast cancer and possibly Alzheimer disease.
组织特异性Expressed in the aorta extrcellular space (at protein level).
疾病相关Ceroid lipofuscinosis, neuronal, 10
序列相似性Belongs to the peptidase A1 family. Contains 1 peptidase A1 domain.
翻译后修饰N- and O-glycosylated.
细胞定位Lysosome. Melanosome. Secreted, extracellular space. Identified by mass spectrometry in melanosome fractions from stage I to stage IV. In aortic samples, detected as an extracellular protein loosely bound to the matrix (PubMed:20551380).