Recombinant人CANT1 protein (ab123189)

概述

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • AccessionQ8WVQ1
    • 种属Human
    • 序列MGSSHHHHHH SSGLVPRGSH MGSHMRPAPG RPPTHNAHNW RLGQAPANWY NDTYPLSPPQ RTPAGIRYRI AVIADLDTES RAQEENTWFS YLKKGYLTLS DSGDKVAVEW DKDHGVLESH LAEKGRGMEL SDLIVFNGKL YSVDDRTGVV YQIEGSKAVP WVILSDGDGT VEKGFKAEWL AVKDERLYVG GLGKEWTTTT GDVVNENPEW VKVVGYKGSV DHENWVSNYN ALRAAAGIQP PGYLIHESAC WSDTLQRWFF LPRRASQERY SEKDDERKGA NLLLSASPDF GDIAVSHVGA VVPTHGFSSF KFIPNTDDQI IVALKSEEDS GRVASYIMAF TLDGRFLLPE TKIGSVKYEG IEFI
    • 分子量41 kDa including tags
    • 氨基酸63 to 401
    • 标签His tag N-Terminus

技术指标

Our Abpromise guarantee covers the use of ab123189 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Mass Spectrometry

    SDS-PAGE

  • 质谱法
    MALDI-TOF
  • 纯度> 90 % SDS-PAGE.
    ab123189 is purified using conventional chromatography techniques.
  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.02% DTT, 0.32% Tris HCl, 10% Glycerol, 0.29% Sodium chloride

常规信息

  • 别名
    • Apyrase
    • Apyrase homolog
    • Ca2+ dependent endoplasmic reticulum nucleoside diphosphatase
    • Calcium activated nucleotidase 1
    • CANT 1
    • CANT1
    • CANT1_HUMAN
    • Putative MAPK activating protein PM09
    • Putative MAPK-activating protein PM09
    • Putative NF kappa B activating protein 107
    • Putative NF-kappa-B-activating protein 107
    • SCAN 1
    • SCAN-1
    • SHAPY
    • Soluble Ca activated nucleotidase isozyme 1
    • Soluble calcium activated nucleotidase 1
    • Soluble calcium activated nucleotidase SCAN 1
    • Soluble calcium-activated nucleotidase 1
    see all
  • 功能Calcium-dependent nucleotidase with a preference for UDP. The order of activity with different substrates is UDP > GDP > UTP > GTP. Has very low activity towards ADP and even lower activity towards ATP. Does not hydrolyze AMP and GMP.
  • 组织特异性Widely expressed.
  • 疾病相关Defects in CANT1 are the cause of Desbuquois dysplasia (DBQD) [MIM:251450]. A chondrodysplasia characterized by severe prenatal and postnatal growth retardation (less than -5 SD), joint laxity, short extremities, progressive scoliosis, round face, midface hypoplasia, prominent bulging eyes. The main radiologic features are short long bones with metaphyseal splay, a 'Swedish key' appearance of the proximal femur (exaggerated trochanter), and advance carpal and tarsal bone age. Two forms of Desbuquois dysplasia are distinguished on the basis of the presence (type 1) or absence (type 2) of characteristic hand anomalies: an extra ossification center distal to the second metacarpal, delta phalanx, bifid distal thumb phalanx, and phalangeal dislocations.
  • 序列相似性Belongs to the apyrase family.
  • 翻译后修饰N-glycosylated.
  • 细胞定位Endoplasmic reticulum membrane. Golgi apparatus > Golgi stack membrane. Processed form: Secreted.
  • Information by UniProt

Recombinant Human CANT1 protein 图像

  • 15% SDS-PAGE showing ab123189 (3µg).

Recombinant Human CANT1 protein (ab123189)参考文献

ab123189 has not yet been referenced specifically in any publications.

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