Recombinant人CaMKI gamma protein (ab51400)

概述

描述

  • 性质Recombinant
  • 来源Baculovirus infected Sf9 cells
  • 氨基酸序列
    • 种属Human
    • 氨基酸1 to 330

相关产品

技术指标

Our Abpromise guarantee covers the use of ab51400 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生物活性Specific activity was determined to be 788 nmol/min/mg.
  • 应用

    SDS-PAGE

    Functional Studies

  • 形式Liquid
  • 补充说明

    ab188554 (CaMKII peptide) can be utilized as a substrate for assessing Kinase activity

  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, pH 7.5

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

常规信息

  • 别名
    • Calcium/calmodulin dependent protein kinase type 1G
    • Calcium/calmodulin-dependent protein kinase I-gamma
    • Calcium/calmodulin-dependent protein kinase Ig
    • Calcium/calmodulin-dependent protein kinase type 1G
    • CaM kinase I gamma
    • CaM kinase IG
    • CaM-KI gamma
    • CaMK like CREB kinase III
    • CaMK-like CREB kinase III
    • Camk1g
    • CaMKI gamma
    • CaMKIG
    • CLICK III
    • CLICK3
    • dJ272L16.1
    • KCC1G_HUMAN
    • VWS1
    see all
  • 功能Calcium/calmodulin-dependent protein kinase belonging to a proposed calcium-triggered signaling cascade. In vitro phosphorylates transcription factor CREB1.
  • 组织特异性Mainly expressed in brain with small amounts in skeletal muscles, kidney, spleen and liver. Strongly expressed in forebrain neocortex, striatum and limbic system.
  • 序列相似性Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.
    Contains 1 protein kinase domain.
  • 结构域The autoinhibitory domain overlaps with the calmodulin binding region and interacts in the inactive folded state with the catalytic domain as a pseudosubstrate.
  • 翻译后修饰May be prenylated on Cys-473.
  • 细胞定位Cytoplasm. Golgi apparatus membrane. Cell membrane.
  • Information by UniProt

Recombinant human CaMKI gamma protein 图像

  • Kinase activity assay. Specific activity 788 nmol/min/mg.
  • Recombinant human CaMKI gamma (with proprietary tag)
    molecular weight 69 kDa.

Recombinant human CaMKI gamma protein (ab51400)参考文献

ab51400 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab51400.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"