Recombinant人CaMKI gamma protein (ab101503)

概述

描述

  • 性质
    Recombinant
  • 来源
    Baculovirus
  • 氨基酸序列
    • Accession
    • 种属
      Human
    • 分子量
      80 kDa including tags
    • 氨基酸
      1 to 476

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技术指标

Our Abpromise guarantee covers the use of ab101503 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生物活性
    The Specific activity of ab101503 was determined to be 820 nmol/min/mg.
  • 应用

    Western blot

    Functional Studies

    SDS-PAGE

  • 纯度
    > 85 % Densitometry.
    The purity was determined to be >85% by densitometry
  • 形式
    Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 10mM Glutathione, 0.25mM DTT, 0.1mM EDTA, 0.1mM PMSF, pH 7.5

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

常规信息

  • 别名
    • Calcium/calmodulin dependent protein kinase type 1G
    • Calcium/calmodulin-dependent protein kinase I-gamma
    • Calcium/calmodulin-dependent protein kinase Ig
    • Calcium/calmodulin-dependent protein kinase type 1G
    • CaM kinase I gamma
    • CaM kinase IG
    • CaM-KI gamma
    • CaMK like CREB kinase III
    • CaMK-like CREB kinase III
    • Camk1g
    • CaMKI gamma
    • CaMKIG
    • CLICK III
    • CLICK3
    • dJ272L16.1
    • KCC1G_HUMAN
    • VWS1
    see all
  • 功能
    Calcium/calmodulin-dependent protein kinase belonging to a proposed calcium-triggered signaling cascade. In vitro phosphorylates transcription factor CREB1.
  • 组织特异性
    Mainly expressed in brain with small amounts in skeletal muscles, kidney, spleen and liver. Strongly expressed in forebrain neocortex, striatum and limbic system.
  • 序列相似性
    Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.
    Contains 1 protein kinase domain.
  • 结构域
    The autoinhibitory domain overlaps with the calmodulin binding region and interacts in the inactive folded state with the catalytic domain as a pseudosubstrate.
  • 翻译后修饰
    May be prenylated on Cys-473.
  • 细胞定位
    Cytoplasm. Golgi apparatus membrane. Cell membrane.
  • Information by UniProt

图片

  • SDS-PAGE analysis of ab101503.
  • The Specific activity of ab101503 was determined to be 820 nmol/min/mg.

文献

ab101503 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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