Recombinant人Calpain 3 protein (ab114576)

概述

描述

  • 性质Recombinant
  • 来源Wheat germ
  • 氨基酸序列
    • AccessionP20807-4
    • 种属Human
    • 序列MHGNKQHLQKDFFLYNASKARSKTYINMREVSQRFRLPPSEYVIVPSTYE PHQEGEFILRVFSEKRNLSEEVENTISVDRPVKKKKTKPIIFVSDRANSN KELGVDQESEEGKGKTSPDKQKQSPQPQPGSSDQESEEQQQFRNIFKQIA GDDMEICADELKKVLNTVVNKHKDLKTHGFTLESCRSMIALMDTDGSGKL NLQEFHHLWNKIKAWQKIFKHYDTDQSGTINSYEMRNAVNDAGFHLNNQL YDIITMRYADKHMNIDFDSFICCFVRLEGMFRAFHAFDKDGDGIIKLNVL EWLQLTMYA
    • 分子量60 kDa including tags
    • 氨基酸1 to 309

技术指标

Our Abpromise guarantee covers the use of ab114576 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

    ELISA

    Western blot

  • 形式Liquid
  • 补充说明Protein concentration is above or equal to 0.05 mg/ml.
    This protein is best used within three months from the date of receipt.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

常规信息

  • 别名
    • Calcium-activated neutral proteinase 3
    • calpain 3, (p94)
    • Calpain L3
    • Calpain large polypeptide L3
    • Calpain p94
    • calpain p94, large [catalytic] subunit
    • calpain, large polypeptide L3
    • Calpain-3
    • CAN3_HUMAN
    • CANP 3
    • CANP3
    • CANPL3
    • CAPN3
    • LGMD 2A
    • LGMD2
    • LGMD2A
    • Lp82
    • Lp85
    • MGC10767
    • MGC11121
    • MGC14344
    • MGC4403
    • Muscle-specific calcium-activated neutral protease 3
    • muscle-specific calcium-activated neutral protease 3 large subunit
    • nCL-1
    • New calpain 1
    • p94
    see all
  • 功能Calcium-regulated non-lysosomal thiol-protease.
  • 组织特异性Isoform I is skeletal muscle specific.
  • 疾病相关Defects in CAPN3 are the cause of limb-girdle muscular dystrophy type 2A (LGMD2A) [MIM:253600]. LGMD2A is an autosomal recessive degenerative myopathy characterized by progressive symmetrical atrophy and weakness of the proximal limb muscles and elevated serum creatine kinase. The symptoms usually begin during the first two decades of life, and the disease gradually worsens, often resulting in loss of walking ability 10 or 20 years after onset.
  • 序列相似性Belongs to the peptidase C2 family.
    Contains 1 calpain catalytic domain.
    Contains 4 EF-hand domains.
  • 细胞定位Cytoplasm.
  • Information by UniProt

Recombinant Human Calpain 3 protein 图像

  • ab114576 on a 12.5% SDS-PAGE Stained with Coomassie Blue.

Recombinant Human Calpain 3 protein (ab114576)参考文献

ab114576 has not yet been referenced specifically in any publications.

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