Recombinant人CALM2 protein (ab116467)

概述

描述

  • 性质
    Recombinant
  • 来源
    Escherichia coli
  • 氨基酸序列
    • Accession
    • 种属
      Human
    • 序列
      MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQ DMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGY ISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK
    • 分子量
      16 kDa
    • 氨基酸
      1 to 149

技术指标

Our Abpromise guarantee covers the use of ab116467 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

    HPLC

  • 纯度
    > 90 % SDS-PAGE.
    ab116467 is purified by proprietary chromatographic techniques. Purity is greater than 90.0% as determined by RP-HPLC and SDS-PAGE analysis.
  • 形式
    Liquid
  • 补充说明
    Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Please see notes section.

    pH: 7.50
    Constituent: 0.32% Tris HCl

常规信息

  • 别名
    • CALM_HUMAN
    • Calm3
    • Calmodulin
    • Calmodulin 2
    • CaM
    • CAMII
    • PHKD
    • PHKD2
    see all
  • 功能
    Calmodulin mediates the control of a large number of enzymes and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases. Together with CEP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis.
  • 序列相似性
    Belongs to the calmodulin family.
    Contains 4 EF-hand domains.
  • 翻译后修饰
    Ubiquitination results in a strongly decreased activity.
    Phosphorylation results in a decreased activity.
  • 细胞定位
    Cytoplasm > cytoskeleton > spindle. Cytoplasm > cytoskeleton > spindle pole. Distributed throughout the cell during interphase, but during mitosis becomes dramatically localized to the spindle poles and the spindle microtubules.
  • Information by UniProt

文献

ab116467 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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