Recombinant人CA12 protein (ab116784)

概述

描述

  • 性质
    Recombinant
  • 来源
    Wheat germ
  • 氨基酸序列
    • Accession
    • 种属
      Human
    • 序列
      APVNGSKWTYFGPDGENSWSKKYPSCGGLLQSPIDLHSDILQYDASLTPL EFQGYNLSANKQFLLTNNGHSVKLNLPSDMHIQGLQSRYSATQLHLHWGN
    • 分子量
      37 kDa including tags
    • 氨基酸
      25 to 124

相关产品

技术指标

Our Abpromise guarantee covers the use of ab116784 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Western blot

    SDS-PAGE

    ELISA

  • 形式
    Liquid
  • 补充说明
    Protein concentration is above or equal to 0.05 mg/ml.
    Best used within three months from the date of receipt.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

常规信息

  • 别名
    • CA 12
    • CA XII
    • CA-XII
    • CA12
    • CAH12_HUMAN
    • Carbonate dehydratase XII
    • Carbonic anhydrase 12
    • Carbonic anhydrase XII
    • Carbonic dehydratase
    • CAXII
    • FLJ20151
    • HsT18816
    • T18816
    • Tumor antigen HOM RCC 3.1.3
    • Tumor antigen HOM-RCC-3.1.3
    see all
  • 功能
    Reversible hydration of carbon dioxide.
  • 组织特异性
    Highly expressed in colon, kidney, prostate, intestine and activated lymphocytes. Expressed at much higher levels in the renal cell cancers than in surrounding normal kidney tissue. Moderately expressed in pancreas, ovary and testis.
  • 疾病相关
    Defects in CA12 are the cause of hyperchlorhidrosis isolated (HCHLH) [MIM:143860]. HCHLH is a disorder characterized by excessive sweating and increased sweat chloride levels. Affected individuals suffer from episodes of hyponatremic dehydration and report increased amounts of visible salt precipitates in sweat.
  • 序列相似性
    Belongs to the alpha-carbonic anhydrase family.
  • 细胞定位
    Membrane.
  • Information by UniProt

图片

  • ab116784 analysed on a 12.5% SDS-PAGE Stained with Coomassie Blue.

文献

ab116784 has not yet been referenced specifically in any publications.

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