Recombinant人C4 binding protein (ab114462)

概述

描述

  • 性质
    Recombinant
  • 来源
    Wheat germ
  • 氨基酸序列
    • Accession
    • 种属
      Human
    • 序列
      MFFWCACCLMVAWRVSASDEHCPELPPVDNSIFVAKEVEGQILGTYVC IKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNV SDKITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGY FEGNNFTLGSTISYYCEDRYYLVGVQEQQCVDGEWSSALPVCKLIQEAPK PECEKALLAFQESKNLCEAMENFMQQLKESGMTMEELKYSLELKKAELKA KLL
    • 分子量
      53 kDa including tags
    • 氨基酸
      1 to 252

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技术指标

Our Abpromise guarantee covers the use of ab114462 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Western blot

    SDS-PAGE

    ELISA

  • 形式
    Liquid
  • 补充说明
    Protein concentration is above or equal to 0.05 mg/ml.
    ab114462 is best used within three months from the date of receipt.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.79% Tris HCl, 0.3% Glutathione

常规信息

  • 别名
    • C4b binding protein beta chain
    • C4b-binding protein beta chain
    • C4BP
    • C4BPB
    • C4BPB_HUMAN
    • Complement component 4 binding protein beta
    • Complement component 4 binding protein beta chain
    • Complement component 4-binding protein beta
    • OTTHUMP00000034288
    • OTTHUMP00000034289
    • OTTHUMP00000034375
    • OTTHUMP0000003474
    • Proline rich protein
    • PRP
    see all
  • 功能
    Controls the classical pathway of complement activation. It binds as a cofactor to C3b/C4b inactivator (C3bINA), which then hydrolyzes the complement fragment C4b. It also accelerates the degradation of the C4bC2a complex (C3 convertase) by dissociating the complement fragment C2a. It also interacts with anticoagulant protein S and with serum amyloid P component. The beta chain binds protein S.
  • 序列相似性
    Contains 3 Sushi (CCP/SCR) domains.
  • 细胞定位
    Secreted.
  • Information by UniProt

Recombinant Human C4 binding protein 图像

  • ab114462 analysed on a 12.5% SDS-PAGE stained with Coomassie Blue.

Recombinant Human C4 binding protein (ab114462)参考文献

ab114462 has not yet been referenced specifically in any publications.

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