Recombinant人C3IP1 protein (ab74979)

概述

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • 种属Human

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技术指标

Our Abpromise guarantee covers the use of ab74979 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Western blot

    ELISA

    SDS-PAGE

  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 20% Glycerol, 50mM Tris acetate, 1mM EDTA, pH 7.5

常规信息

  • 别名
    • C3IP1
    • CUL3 interacting protein 1
    • CUL3-interacting protein 1
    • DKIR
    • DKIR homolog
    • FLJ27152
    • hDKIR
    • Kelch like 12
    • Kelch like 12 (Drosophila)
    • Kelch like 12 variant
    • Kelch like protein 12
    • Kelch like protein C3IP1
    • kelch-like family member 12
    • Kelch-like protein 12
    • KLH12_HUMAN
    • KLHL 12
    • klhl12
    • OTTHUMP00000038799
    see all
  • 功能Serves as a substrate-specific adapter for the CUL3-based ubiquitin-protein E3 ligase complex. Negatively regulates the Wnt signaling pathway via the targeted ubiquitination and subsequent proteolysis of DVL3.
  • 组织特异性Highly expressed in testis and at lower levels in the submandibular salivary gland.
  • 序列相似性Contains 1 BTB (POZ) domain.
    Contains 6 Kelch repeats.
  • 结构域The BTB domain is required for interaction with CUL3.
  • Information by UniProt

Recombinant Human C3IP1 protein 图像

  • SDS-PAGE showing ab74979 at approximately 65kDa.

Recombinant Human C3IP1 protein (ab74979)参考文献

ab74979 has not yet been referenced specifically in any publications.

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