来源 Escherichia coli
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Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Constituents: 20% Glycerol, 50mM Tris acetate, 1mM EDTA, pH 7.5
CUL3 interacting protein 1
CUL3-interacting protein 1
功能 Serves as a substrate-specific adapter for the CUL3-based ubiquitin-protein E3 ligase complex. Negatively regulates the Wnt signaling pathway via the targeted ubiquitination and subsequent proteolysis of DVL3.
组织特异性 Highly expressed in testis and at lower levels in the submandibular salivary gland.
序列相似性 Contains 1 BTB (POZ) domain. Contains 6 Kelch repeats.
结构域 The BTB domain is required for interaction with CUL3.
Information by UniProt
Recombinant Human C3IP1 protein 图像
Recombinant Human C3IP1 protein (ab74979)参考文献
has not yet been referenced specifically in any publications.
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