Recombinant人C1orf19 protein (ab124991)

概述

  • 产品名称Recombinant人C1orf19 protein
  • 蛋白长度Full length protein

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • AccessionQ8WW01
    • 种属Human
    • 序列MGSSHHHHHH SSGLVPRGSH MEERGDSEPT PGCSGLGPDG VRGFGDGGGA PSWAPEDAWM GTHPKYLEMM ELDIGDATHV YVAFLVYLDL MESKSWHEVN CVGLPELQLI CLVGTEIEGE GLQTVVPTPI TASLSHNRIR EILKASRKLQ GDPDLPMSFT LAIVESDSTI VYYKLTDGFM LPDPQNISLR R
    • 分子量21 kDa including tags
    • 氨基酸1 to 171
    • 标签His tag N-Terminus

技术指标

Our Abpromise guarantee covers the use of ab124991 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

  • 纯度> 90 % SDS-PAGE.
    ab124991 is purified by proprietary chromatographic techniques.
  • 形式Liquid
  • 补充说明b124991 should be stored desiccated below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Store at -20°C. Store under Desiccating conditions.

    pH: 8.00
    Constituents: 0.03% DTT, 0.32% Tris HCl, 20% Glycerol, 1.17% Sodium chloride

常规信息

  • 别名
    • Chromosome 1 open reading frame 19
    • Chromosome 1 open reading frame 19, isoform CRA_c
    • HsSen15
    • sen15
    • SEN15 homolog
    • SEN15_HUMAN
    • tRNA intron endonuclease Sen15
    • tRNA splicing endonuclease 15 homolog (S. cerevisiae)
    • tRNA splicing endonuclease subunit Sen15
    • tRNA-intron endonuclease SEN15
    • tRNA-splicing endonuclease subunit SEN15
    • Tsen15
    see all
  • 功能Non-catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5' and 3' splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body. The tRNA splicing endonuclease is also involved in mRNA processing via its association with pre-mRNA 3' end processing factors, establishing a link between pre-tRNA splicing and pre-mRNA 3' end formation, suggesting that the endonuclease subunits function in multiple RNA-processing events.
  • 组织特异性Widely expressed. Highly expressed in testis and uterus.
  • 序列相似性Belongs to the SEN15 family.
  • 细胞定位Nucleus. Nucleus > nucleolus. May be transiently localized in the nucleolus.
  • Information by UniProt

Recombinant Human C1orf19 protein (ab124991)参考文献

ab124991 has not yet been referenced specifically in any publications.

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