Recombinant人beta Synuclein protein (ab82630)

概述

描述

  • 性质
    Recombinant
  • 来源
    Escherichia coli
  • 氨基酸序列
    • 种属
      Human

技术指标

Our Abpromise guarantee covers the use of ab82630 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

  • 纯度
    > 95 % SDS-PAGE.

  • 形式
    Lyophilised
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot. Store at -80°C. Avoid freeze / thaw cycle.

    Preservative: None
    Constituents: PBS, pH 7.4

  • 复溶
    Reconstitute in PBS, pH 7.4, Packaging size : 0.2 mg

常规信息

  • 别名
    • 14 kDa brain-specific protein
    • Beta-synuclein
    • Phosphoneuroprotein 14
    • PNP14
    • Sncb
    • Synuclein beta
    • SYUB_HUMAN
    see all
  • 功能
    Non-amyloid component of senile plaques found in Alzheimer disease. Could act as a regulator of SNCA aggregation process. Protects neurons from staurosporine and 6-hydroxy dopamine (6OHDA)-stimulated caspase activation in a p53/TP53-dependent manner. Contributes to restore the SNCA anti-apoptotic function abolished by 6OHDA. Not found in the Lewy bodies associated with Parkinson disease.
  • 组织特异性
    Expressed predominantly in brain; concentrated in presynaptic nerve terminals.
  • 序列相似性
    Belongs to the synuclein family.
  • 翻译后修饰
    Phosphorylated. Phosphorylation by G-protein coupled receptor kinases (GRK) is more efficient than phosphorylation by CK1, CK2 and CaM-kinase II.
  • 细胞定位
    Cytoplasm.
  • Information by UniProt

图片

  • ab82630 at 1µg on SDS-PAGE.

文献

ab82630 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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