Recombinant人beta-cardiac myosin heavy chain protein (ab112326)

概述

描述

  • 性质Recombinant
  • 来源Wheat germ
  • 氨基酸序列
    • AccessionP12883
    • 种属Human
    • 序列MGDSEMAVFGAAAPYLRKSEKERLEAQTRPFDLKKDVFVPDDKQEFVKAK IVSREGGKVTAETEYGKTVTVKEDQVMQQNPPKFDKIEDMAMLTFLHEPA VLYNLKDRY
    • 分子量38 kDa including tags
    • 氨基酸1 to 109
    • 标签GST tag N-Terminus

技术指标

Our Abpromise guarantee covers the use of ab112326 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    ELISA

    Western blot

    SDS-PAGE

  • 形式Liquid
  • 补充说明Best use within three months from the date of receipt of this protein.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.79% Tris HCl, 0.31% Glutathione

常规信息

  • 别名
    • cardiomyopathy, hypertrophic 1
    • CMD1S
    • CMH1
    • MPD1
    • MyHC beta
    • MYHCB
    • Myosin heavy chain, cardiac muscle beta isoform
    • myosin, heavy polypeptide 7, cardiac muscle, beta
    see all
  • 相关性Muscle myosin is a hexameric protein that consists of 2 heavy chain subunits (MHC), 2 alkali light chain subunits (MLC) and 2 regulatory light chain subunits (MLC-2). Cardiac MHC exists as two isoforms in humans, alpha-cardiac MHC and beta-cardiac MHC. These two isoforms are expressed in different amounts in the human heart. During normal physiology, beta-cardiac MHC is the predominant form, with the alpha-isoform contributing around only 7% of the total MHC. Mutations of the MHC genes are associated with several different dilated and hypertrophic cardiomyopathies.
  • 细胞定位Thick filaments of the myofibrils.

Recombinant Human beta-cardiac myosin heavy chain protein 图像

  • ab112326 analysed on a 12.5% SDS-PAGE gel stained with Coomassie Blue.

Recombinant Human beta-cardiac myosin heavy chain protein (ab112326)参考文献

ab112326 has not yet been referenced specifically in any publications.

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