Recombinant人BCMA protein (ab50089)

概述

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • 种属Human
    • 序列AGQCSQNEYF DSLLHACIPC QLRCSSNTPP LTCQRYCNAS VTNSVKGTNA
    • 氨基酸5 to 54

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技术指标

Our Abpromise guarantee covers the use of ab50089 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

  • 内毒素水平< 0.100 Eu/µg
  • 纯度> 95 % SDS-PAGE.
    ab50089 purity was evaluated also by HPLC. Endotoxin level is less than 0.1 ng per µg (1EU/µg).
  • 形式Lyophilised
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. The lyophilized protein is stable for a few weeks at room temperature. Store at -20°C long term.

  • 复溶Reconstitute to 1mg/ml with distilled water.

常规信息

  • 别名
    • B cell maturation antigen
    • B cell maturation factor
    • B cell maturation protein
    • B-cell maturation protein
    • BCM
    • BCMA
    • CD269
    • CD269 antigen
    • TNFRSF17
    • TNR17_HUMAN
    • Tumor necrosis factor receptor superfamily member 17
    see all
  • 功能Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates NF-kappa-B and JNK.
  • 组织特异性Expressed in mature B-cells, but not in T-cells or monocytes.
  • 疾病相关Note=A chromosomal aberration involving TNFRSF17 is found in a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(4;16)(q26;p13) with IL2.
  • 序列相似性Contains 1 TNFR-Cys repeat.
  • 细胞定位Cell membrane. Endomembrane system. Perinuclear Golgi-like structures.
  • Information by UniProt

Recombinant Human BCMA protein (ab50089)参考文献

ab50089 has not yet been referenced specifically in any publications.

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Abreviews
Application ELISA
ab50089 was coated overnight at 4 degrees C at a concentration of 2 ug/mL. The goat anti-human BCMA antibody AF193 was used at a concentration of 1 ug/mL and incubated for 1 hour at room temperature to detect ab50089. 1% milk in TBST was used as the blocking agent and diluent. Excellent signal over background was observed. The average of eight replicates is shown with standard deviation included by error bars.
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提交于 Feb 22 2016

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"