Recombinant人BAPX1 protein (ab114496)

概述

  • 产品名称Recombinant人BAPX1 protein
  • 蛋白长度Protein fragment

描述

  • 性质Recombinant
  • 来源Wheat germ
  • 氨基酸序列
    • Accessionp78367
    • 种属Human
    • 序列RLFGERDAGALGGAEDSLLASPAGTRTAAGRTAESPEGWDSDSALSEENE SRRRCADAR
    • 分子量32 kDa including tags
    • 氨基酸53 to 111

技术指标

Our Abpromise guarantee covers the use of ab114496 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    ELISA

    SDS-PAGE

    Western blot

  • 形式Liquid
  • 补充说明Protein concentration is above or equal to 0.05 mg/ml. This protein is best used within three months from the date of receipt.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

常规信息

  • 别名
    • Bagpipe homeobox 1
    • Bagpipe homeobox homolog 1
    • Bagpipe homeobox protein homolog 1
    • Bagpipe homeobox, Drosophila, homolog of, 1
    • BAPX 1
    • Homeobox protein NK-3 homolog B
    • Homeobox protein Nkx 3.2
    • Homeobox protein Nkx-3.2
    • MGC138171
    • NK3 homeobox 2
    • NKX3 2
    • NKX3-2
    • NKX3.2
    • NKX3.2, mouse, homolog of
    • NKX32_HUMAN
    • NKX3B
    • OTTHUMP00000115816
    • SMMD
    see all
  • 功能Transcriptional repressor that acts as a negative regulator of chondrocyte maturation. PLays a role in distal stomach development; required for proper antral-pyloric morphogenesis and development of antral-type epithelium. In concert with GSC, defines the structural components of the middle ear; required for tympanic ring and gonium development and in the regulation of the width of the malleus.
  • 组织特异性Expressed at highest levels in cartilage, bone (osteosarcoma) and gut (small intestine and colon), whereas moderate expression is seen in trachea and brain. Expressed in visceral mesoderm and embryonic skeleton.
  • 疾病相关Defects in NKX3-2 are the cause of spondylo-megaepiphyseal-metaphyseal dysplasia (SMMD) [MIM:613330]. It is a skeletal dysplasia characterized by disproportionate short stature with a short and stiff neck and trunk, relatively long limbs that may show flexion contractures of the distal joints, delayed and impaired ossification of the vertebral bodies, the presence of large epiphysea ossification centers and wide growth plates in the long tubular bones and numerous pseudoepiphyses of the short tubular bones in hands and feet.
  • 序列相似性Belongs to the NK-3 homeobox family.
    Contains 1 homeobox DNA-binding domain.
  • 细胞定位Nucleus.
  • Information by UniProt

Recombinant Human BAPX1 protein 图像

  • ab114496 analysed by 12.5% SDS-PAGE and stained with Coomassie Blue.

Recombinant Human BAPX1 protein (ab114496)参考文献

ab114496 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab114496.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"