Recombinant人Bak protein (ab114337)

概述

描述

  • 性质
    Recombinant
  • 来源
    Wheat germ
  • 氨基酸序列
    • Accession
    • 种属
      Human
    • 序列
      MASGQGPGPPRQECGEPALPSASEEQVAQDTEEVFRSYVFYRHQQEQEAE GVAAPADPEMVTLPLQPSSTMGQVGRQLAIIGDDINRRYDSEFQTMLQHL QPTAENAYEYFTKIATSLFESGINWGRVVALLGFGYRLALHVYQHGLTGF LGQVTRFVVDFMLHHCIARWIAQRGGWVAALNLGNGPILNVLVVLGVVLL GQFVVRRFFKS
    • 分子量
      49 kDa including tags
    • 氨基酸
      1 to 211

技术指标

Our Abpromise guarantee covers the use of ab114337 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Western blot

    SDS-PAGE

    ELISA

  • 形式
    Liquid
  • 补充说明
    Protein concentration is above or equal to 0.05 mg/ml.
    Best used within three months from the date of receipt.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

常规信息

  • 别名
    • Apoptosis regulator BAK
    • BAK
    • BAK like
    • Bak NT
    • BAK_HUMAN
    • Bak1
    • Bcl 2 homologous antagonist/killer
    • Bcl 2 like 7 protein
    • Bcl-2 homologous antagonist/killer
    • Bcl-2-like protein 7
    • BCL2 antagonist/killer 1
    • Bcl2 like 7 Protein
    • Bcl2-L-7
    • BCL2L7
    • CDN1
    • Cell death inhibitor 1
    • MGC117255
    • MGC3887
    • NBak
    • Pro apoptotic protein BAK
    see all
  • 功能
    In the presence of an appropriate stimulus, accelerates programmed cell death by binding to, and antagonizing the anti-apoptotic action of BCL2 or its adenovirus homolog E1B 19k protein. Low micromolar levels of zinc ions inhibit the promotion of apoptosis.
  • 组织特异性
    Expressed in a wide variety of tissues, with highest levels in the heart and skeletal muscle.
  • 序列相似性
    Belongs to the Bcl-2 family.
  • 结构域
    Intact BH3 motif is required by BIK, BID, BAK, BAD and BAX for their pro-apoptotic activity and for their interaction with anti-apoptotic members of the Bcl-2 family.
  • 细胞定位
    Mitochondrion membrane.
  • Information by UniProt

图片

  • ab114337 analysed on a 12.5% SDS-PAGE gel stained with Coomassie Blue

文献

ab114337 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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