Recombinant人BAFF protein (ab109136)

概述

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • AccessionQ9Y275
    • 种属Human
    • 分子量23 kDa including tags
    • 氨基酸134 to 285
    • 标签DDDDK tag N-Terminus

技术指标

Our Abpromise guarantee covers the use of ab109136 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生物活性Binds to Human and Mouse BAFFR, TACI and BCMA. Relative binding affinity (EC50) for BAFFR (Human): ~3ng/ml.
  • 应用

    SDS-PAGE

  • 内毒素水平< 0.100 Eu/µg
  • 纯度> 95 % SDS-PAGE.

  • 形式Lyophilised
  • 补充说明After reconstitution, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles. PBS containing at least 0.1% BSA should be used for further dilutions.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C.

    Preservative: None
    Constituents: PBS

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

  • 复溶Reconstitute with 100µl sterile water to give a final concentration of 0.1mg/ml.

常规信息

  • 别名
    • ApoL related ligand TALL 1
    • B cell Activating Factor
    • B lymphocyte stimulator
    • B-cell-activating factor
    • BAFF
    • BLyS
    • CD 257
    • CD257
    • CD257 antigen
    • Delta BAFF
    • Dendritic cell derived TNF like molecule
    • Dendritic cell-derived TNF-like molecule
    • DTL
    • DTL precursor
    • PRO738
    • soluble form
    • TALL 1
    • TALL-1
    • TALL1
    • THANK
    • TN13B_HUMAN
    • TNF and APOL related leukocyte expressed ligand 1
    • TNF homolog that activates apoptosis
    • TNF homolog that activates apoptosis NKFB and JNK.
    • TNF- and APOL-related leukocyte expressed ligand 1
    • TNFSF13B
    • TNFSF20
    • Tumor necrosis factor (ligand) superfamily member 13b
    • Tumor necrosis factor ligand superfamily member 13b
    • Tumor necrosis factor ligand superfamily member 20
    • Tumor necrosis factor like protein ZTNF4
    • Tumor necrosis factor superfamily member 13B
    • UNQ401
    • ZTNF4
    see all
  • 功能Cytokine that binds to TNFRSF13B/TACI and TNFRSF17/BCMA. TNFSF13/APRIL binds to the same 2 receptors. Together, they form a 2 ligands -2 receptors pathway involved in the stimulation of B-and T-cell function and the regulation of humoral immunity. A third B-cell specific BAFF-receptor (BAFFR/BR3) promotes the survival of mature B-cells and the B-cell response.
  • 组织特异性Abundantly expressed in peripheral blood Leukocytes and is specifically expressed in monocytes and macrophages. Also found in the spleen, lymph node, bone marrow, T-cells and dendritic cells. A lower expression seen in placenta, heart, lung, fetal liver, thymus, and pancreas.
  • 序列相似性Belongs to the tumor necrosis factor family.
  • 翻译后修饰The soluble form derives from the membrane form by proteolytic processing.
    N-glycosylated.
  • 细胞定位Secreted and Cell membrane.
  • Information by UniProt

Recombinant human BAFF protein (ab109136)参考文献

ab109136 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab109136.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"