The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Shipped at 4°C. Store at -20°C.
Constituents: 0.32% Tris HCl, 0.58% Sodium chloride
Reconstitute with water to desired concentration.
ABC C transporter
ABC transporter 3
ATP binding cassette 3
ATP binding cassette sub family A (ABC1) member 3
ATP binding cassette sub family A member 3
ATP binding cassette transporter 3
ATP-binding cassette 3
ATP-binding cassette sub-family A member 3
ATP-binding cassette transporter 3
CED7. C. elegans, homolog of
P180 Lamellar Body Protein
Plays an important role in the formation of pulmonary surfactant, probably by transporting lipids such as cholesterol.
Highly expressed in lung, followed by brain, pancreas, skeletal muscle and heart. Weakly expressed in placenta, kidney and liver. Also expressed in medullary thyroid carcinoma cells (MTC) and in C-cell carcinoma.
Defects in ABCA3 are the cause of pulmonary surfactant metabolism dysfunction type 3 (SMDP3) [MIM:610921]; also called pulmonary alveolar proteinosis due to ABCA3 deficiency. A rare lung disorder due to impaired surfactant homeostasis. It is characterized by alveolar filling with floccular material that stains positive using the periodic acid-Schiff method and is derived from surfactant phospholipids and protein components. Excessive lipoproteins accumulation in the alveoli results in severe respiratory distress.
Belongs to the ABC transporter superfamily. ABCA family. Contains 2 ABC transporter domains.
Multifunctional polypeptide with two homologous halves, each containing an hydrophobic membrane-anchoring domain and an ATP binding cassette (ABC) domain.