Recombinant人ATG4B protein (ab123195)

概述

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • AccessionQ9Y4P1
    • 种属Human
    • 序列MDAATLTYDT LRFAEFEDFP ETSEPVWILG RKYSIFTEKD EILSDVASRL WFTYRKNFPA IGGTGPTSDT GWGCMLRCGQ MIFAQALVCR HLGRDWRWTQ RKRQPDSYFS VLNAFIDRKD SYYSIHQIAQ MGVGEGKSIG QWYGPNTVAQ VLKKLAVFDT WSSLAVHIAM DNTVVMEEIR RLCRTSVPCA GATAFPADSD RHCNGFPAGA EVTNRPSPWR PLVLLIPLRL GLTDINEAYV ETLKHCFMMP QSLGVIGGKP NSAHYFIGYV GEELIYLDPH TTQPAVEPTD GCFIPDESFH CQHPPCRMSI AELDPSIAVG FFCKTEDDFN DWCQQVKKLS LLGGALPMFE LVEQQPSHLA CPDVLNLSLD SSDVERLERF FDSEDEDFEI LSLLEHHHHH H
    • 分子量45 kDa including tags
    • 氨基酸1 to 393
    • 标签His tag C-Terminus

技术指标

Our Abpromise guarantee covers the use of ab123195 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

    Mass Spectrometry

  • 质谱法
    MALDI-TOF
  • 纯度> 90 % SDS-PAGE.
    ab123195 is purified using conventional chromatography techniques.
  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.002% PMSF, 0.02% DTT, 0.32% Tris HCl, 20% Glycerol

常规信息

  • 别名
    • APG4 autophagy 4 homolog B
    • APG4B
    • ATG4 autophagy related 4 homolog B (S. cerevisiae)
    • ATG4B
    • ATG4B_HUMAN
    • AUT like 1 cysteine endopeptidase
    • AUT-like 1 cysteine endopeptidase
    • AUTL1
    • Autophagin 1
    • Autophagin-1
    • Autophagy related cysteine endopeptidase 1
    • Autophagy related protein 4 homolog B
    • Autophagy-related cysteine endopeptidase 1
    • Autophagy-related protein 4 homolog B
    • Cysteine protease ATG4B
    • hAPG4B
    • MGC1353
    see all
  • 功能Cysteine protease required for autophagy, which cleaves the C-terminal part of either MAP1LC3, GABARAPL2 or GABARAP, allowing the liberation of form I. A subpopulation of form I is subsequently converted to a smaller form (form II). Form II, with a revealed C-terminal glycine, is considered to be the phosphatidylethanolamine (PE)-conjugated form, and has the capacity for the binding to autophagosomes.
  • 组织特异性Mainly expressed in the skeletal muscle, followed by brain, heart, liver and pancreas.
  • 序列相似性Belongs to the peptidase C54 family.
  • 细胞定位Cytoplasm.
  • Information by UniProt

Recombinant Human ATG4B protein 图像

  • 15% SDS-PAGE showing ab123195 (3µg).

Recombinant Human ATG4B protein (ab123195)参考文献

ab123195 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab123195.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"