Recombinant人ATF2 protein (ab43598)

概述

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • 种属Human
    • 序列MSDDKPFLCT APGCGQRFTN EDHLAVHKHK HEMTLKFGPA RNDSVIVADQ TPTPTRFLKN CEEVGLFNEL ASPFENEFKK ASEDDIKKMP LDLSPLATPI IRSKIEEPSV VETTHQDSPL PHPESTTSDE KEVPLAQTAQ PTSAIVRPAS LQVPNVLLTS SDSSVIIQQA VPSPTSSTVI TQAPSSNRPI VPVPGPFPLL LHLPNGQTMP VAIPASITSS NVHVPAAVPL VRPVTMVPSV PGIPGPSSPQ PVQS
    • 氨基酸1 to 254

技术指标

Our Abpromise guarantee covers the use of ab43598 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Functional Studies

  • 形式Liquid
  • 补充说明

    ab43598 (Human ATF2 protein fragment) can be utilized as a substrate for ab60304 (Active mouse JNK1 full length protein)

  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 0.25mM DTT, 0.1mM PMSF, pH 7.5

常规信息

  • 别名
    • Activating transcription factor 2
    • Activating transcription factor 2 splice variant ATF2 var2
    • ATF 2
    • Atf-2
    • Atf2
    • ATF2 protein
    • ATF2_HUMAN
    • cAMP Response Element Binding Protein 2
    • cAMP response element binding protein CRE BP1
    • cAMP response element-binding protein CRE-BP1
    • cAMP responsive element binding protein 2, formerly
    • cAMP-dependent transcription factor ATF-2
    • cAMP-responsive element-binding protein 2
    • CRE BP1
    • CRE-BP
    • CREB 2
    • CREB-2
    • CREB2
    • CREBP1
    • Cyclic AMP dependent transcription factor ATF 2
    • Cyclic AMP-dependent transcription factor ATF-2
    • Cyclic AMP-responsive element-binding protein 2
    • D130078H02Rik
    • D18875
    • HB 16
    • HB16
    • Histone acetyltransferase ATF2
    • MGC105211
    • MGC105222
    • MGC111558
    • MGC142504
    • mXBP
    • MXBP protein
    • Tg(Gzma-Klra1)7Wum
    • TREB 7
    • TREB7
    see all
  • 功能Transcriptional activator, probably constitutive, which binds to the cAMP-responsive element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Interaction with JUN redirects JUN to bind to CRES preferentially over the 12-O-tetradecanoylphorbol-13-acetate response elements (TRES) as part of an ATF2/JUN complex.
  • 组织特异性Abundant expression seen in the brain.
  • 序列相似性Belongs to the bZIP family. ATF subfamily.
    Contains 1 bZIP domain.
    Contains 1 C2H2-type zinc finger.
  • 翻译后修饰Phosphorylation of Thr-69 and Thr-71 by MAPK14 causes increased transcriptional activity. Also phosphorylated and activated by JNK.
  • 细胞定位Nucleus.
  • Information by UniProt

Recombinant Human ATF2 protein (ab43598)参考文献

ab43598 has not yet been referenced specifically in any publications.

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