重组人ATF2蛋白(ab43598)
Key features and details
- Expression system: Escherichia coli
- Purity: > 80% Densitometry
- Tags: GST tag N-Terminus
- Suitable for: Functional Studies
描述
-
产品名称
重组人ATF2蛋白 -
纯度
> 80 % Densitometry. -
表达系统
Escherichia coli -
Accession
-
蛋白长度
Protein fragment -
无动物成分
No -
性质
Recombinant -
-
种属
Human -
序列
MSDDKPFLCT APGCGQRFTN EDHLAVHKHK HEMTLKFGPA RNDSVIVADQ TPTPTRFLKN CEEVGLFNEL ASPFENEFKK ASEDDIKKMP LDLSPLATPI IRSKIEEPSV VETTHQDSPL PHPESTTSDE KEVPLAQTAQ PTSAIVRPAS LQVPNVLLTS SDSSVIIQQA VPSPTSSTVI TQAPSSNRPI VPVPGPFPLL LHLPNGQTMP VAIPASITSS NVHVPAAVPL VRPVTMVPSV PGIPGPSSPQ PVQS -
氨基酸
1 to 254 -
标签
GST tag N-Terminus
-
相关产品
-
Recombinant Protein
技术指标
Our Abpromise guarantee covers the use of ab43598 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
-
应用
Functional Studies
-
形式
Liquid -
补充说明
ab43598 (Human ATF2 protein fragment) can be utilized as a substrate for ab60304 (Active mouse JNK1 full length protein)
-
Concentration information loading...
制备和贮存
-
稳定性和存储
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 7.50
Constituents: 0.00174% PMSF, 0.00385% DTT, 0.79% Tris HCl, 25% Glycerol (glycerin, glycerine), 0.87% Sodium chloride
常规信息
-
别名
- Activating transcription factor 2
- Activating transcription factor 2 splice variant ATF2 var2
- ATF 2
see all -
功能
Transcriptional activator, probably constitutive, which binds to the cAMP-responsive element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Interaction with JUN redirects JUN to bind to CRES preferentially over the 12-O-tetradecanoylphorbol-13-acetate response elements (TRES) as part of an ATF2/JUN complex. -
组织特异性
Abundant expression seen in the brain. -
序列相似性
Belongs to the bZIP family. ATF subfamily.
Contains 1 bZIP domain.
Contains 1 C2H2-type zinc finger. -
翻译后修饰
Phosphorylation of Thr-69 and Thr-71 by MAPK14 causes increased transcriptional activity. Also phosphorylated and activated by JNK. -
细胞定位
Nucleus. - Information by UniProt
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
-
SDS download
-
Datasheet download
文献 (0)
ab43598 尚未被引用在任何文献中。