Recombinant人ASPA protein (ab123155)

概述

  • 产品名称
    Recombinant人ASPA protein
  • 蛋白长度
    Full length protein

描述

  • 性质
    Recombinant
  • 来源
    Escherichia coli
  • 氨基酸序列
    • Accession
    • 种属
      Human
    • 序列
      MGSSHHHHHH SSGLVPRGSH MGSMTSCHIAEEH IQKVAIFGGT HGNELTGVFL VKHWLENGAE IQRTGLEVKP FITNPRAVKK CTRYIDCDLN RIFDLENLGK KMSEDLPYEV RRAQEINHLF GPKDSEDSYD IIFDLHNTTS NMGCTLILED SRNNFLIQMF HYIKTSLAPL PCYVYLIEHP SLKYATTRSI AKYPVGIEVG PQPQGVLRAD ILDQMRKMIK HALDFIHHFN EGKEFPPCAI EVYKIIEKVD YPRDENGEIA AIIHPNLQDQ DWKPLHPGDP MFLTLDGKTI PLGGDCTVYP VFVNEAAYYE KKEAFAKTTK LTLNAKSIRC CLH
    • 分子量
      38 kDa including tags
    • 氨基酸
      1 to 313
    • 标签
      His tag N-Terminus

技术指标

Our Abpromise guarantee covers the use of ab123155 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Mass Spectrometry

    SDS-PAGE

  • 质谱法
    MALDI-TOF
  • 纯度
    > 90 % SDS-PAGE.
    ab123155 was purified by using conventional chromatography.
  • 形式
    Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 0.002% PMSF, 0.02% DTT, 0.32% Tris HCl, 20% Glycerol, 0.58% Sodium chloride

常规信息

  • 别名
    • ACY 2
    • ACY-2
    • ACY2
    • ACY2_HUMAN
    • Aminoacylase 2
    • Aminoacylase-2
    • Aminoacylase2
    • ASP
    • ASPA
    • Aspartoacylase
    • Aspartoacylase (aminoacylase 2, Canavan disease)
    • Aspartoacylase (Canavan disease)
    • NUR 7
    • NUR7
    • OTTMUSP00000006437
    • RP23-213I10.1
    • Small lethargic
    see all
  • 功能
    Catalyzes the deacetylation of N-acetylaspartic acid (NAA) to produce acetate and L-aspartate. NAA occurs in high concentration in brain and its hydrolysis NAA plays a significant part in the maintenance of intact white matter. In other tissues it act as a scavenger of NAA from body fluids.
  • 组织特异性
    Brain white matter, skeletal muscle, kidney, adrenal glands, lung and liver.
  • 疾病相关
    Defects in ASPA are the cause of Canavan disease (CAND) [MIM:271900]; also known as spongy degeneration of the brain. CAND is a rare neurodegenerative condition of infancy or childhood characterized by white matter vacuolization and demeylination that gives rise to a spongy appearance. The clinical features are onset in early infancy, atonia of neck muscles, hypotonia, hyperextension of legs and flexion of arms, blindness, severe mental defect, megalocephaly, and death by 18 months on the average.
  • 序列相似性
    Belongs to the AspA/AstE family. Aspartoacylase subfamily.
  • 细胞定位
    Cytoplasm. Nucleus.
  • Information by UniProt

Recombinant Human ASPA protein 图像

  • 15% SDS-PAGE analysis of ab123155 (3 µg).

Recombinant Human ASPA protein (ab123155)参考文献

ab123155 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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