Recombinant人ASF1A protein (ab84211)

概述

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • 种属Human
    • 序列MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSMAKV QVNNVVVLDN PSPFYNPFQF EITFECIEDL SEDLEWKIIY VGSAESEEYD QVLDSVLVGP VPAGRHMFVF QADAPNPGLI PDADAVGVTV VLITCTYRGQ EFIRVGYYVN NEYTETELRE NPPVKPDFSK LQRNILASNP RVTRFHINWE DNTEKLEDAE SSNPNLQSLL STDALPSASK GWSTSENSLN VMLESHMDCM

技术指标

Our Abpromise guarantee covers the use of ab84211 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

  • 纯度> 90 % SDS-PAGE.
    ab84211 is purified using conventional chromatography techniques.
  • 形式Liquid
  • 补充说明Endotoxin Level: < 1.0 EU per 1 µg of protein (determined by LAL method).
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Preservative: None
    Constituents: 10% Glycerol, 20mM Tris HCl, 1mM DTT, pH 8.0

常规信息

  • 别名
    • Anti silencing function 1A
    • Anti-silencing function protein 1 homolog A
    • ASF1 anti silencing function 1 homolog A
    • ASF1 anti silencing function 1 homolog A (S. cerevisiae)
    • asf1a
    • ASF1A_HUMAN
    • CCG1 interacting factor A
    • CCG1-interacting factor A
    • CGI 98
    • CIA
    • hAsf1
    • hAsf1a
    • hCIA
    • Histone chaperone ASF1A
    • HSPC146
    see all
  • 功能Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly. Cooperates with chromatin assembly factor 1 (CAF-1) to promote replication-dependent chromatin assembly and with HIRA to promote replication-independent chromatin assembly. Required for the formation of senescence-associated heterochromatin foci (SAHF) and efficient senescence-associated cell cycle exit.
  • 组织特异性Ubiquitously expressed.
  • 序列相似性Belongs to the ASF1 family.
  • 翻译后修饰Phosphorylated by TLK1 and TLK2. Highly phosphorylated in S-phase and at lower levels in M-phase.
  • 细胞定位Nucleus.
  • Information by UniProt

Recombinant Human ASF1A protein 图像

  • 15% SDS-PAGE showing ab84211 at approximately 27kDa (3µg).

Recombinant Human ASF1A protein (ab84211)参考文献

ab84211 has not yet been referenced specifically in any publications.

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