Recombinant人ASAH1 protein (ab114948)

概述

  • 产品名称Recombinant人ASAH1 protein
  • 蛋白长度Protein fragment

描述

  • 性质Recombinant
  • 来源Wheat germ
  • 氨基酸序列
    • AccessionQ13510
    • 种属Human
    • 序列PPWTEDCRKSTYPPSGPTYRGAVPWYTINLDLPPYKRWHELMLDKAPMLK VIVNSLKNMINTFVPSGKVMQVVDEKLPGLLGNFPGPFEEEMKGIAAVTD
    • 分子量37 kDa including tags
    • 氨基酸25 to 124

相关产品

技术指标

Our Abpromise guarantee covers the use of ab114948 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    ELISA

    SDS-PAGE

    Western blot

  • 形式Liquid
  • 补充说明Protein concentration is above or equal to 0.05 mg/ml.
    Best used within three months from the date of receipt.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

常规信息

  • 别名
    • AC
    • ACDase
    • Acid CDase
    • Acid ceramidase
    • Acid ceramidase precursor
    • Acid ceramidase subunit beta
    • Acylsphingosine deacylase
    • ASAH
    • ASAH 1
    • ASAH1
    • ASAH1_HUMAN
    • FLJ21558
    • FLJ22079
    • N acylsphingosine amidohydrolase
    • N acylsphingosine amidohydrolase (acid ceramidase) 1
    • N acylsphingosine amidohydrolase 1
    • N-acylsphingosine amidohydrolase
    • N-acylsphingosine deacylase
    • PHP
    • PHP32
    • Putative 32 kDa heart protein
    • SMAPME
    see all
  • 功能Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.
  • 组织特异性Broadly expressed with highest expression in heart.
  • 疾病相关Defects in ASAH1 are the cause of Farber lipogranulomatosis (FL) [MIM:228000]; also known as Farber disease (FD). This sphingolipid disease is characterized by subcutaneous lipid-loaded nodules, excruciating pain in the joints and extremities, marked accumulation of ceramide in lysosomes, and death by three years of age.
  • 序列相似性Belongs to the acid ceramidase family.
  • 细胞定位Lysosome.
  • Information by UniProt

Recombinant Human ASAH1 protein 图像

  • 12.5% SDS-PAGE showing ab114948 at approximately 36.63kDa.
    Stained with Coomassie Blue.

Recombinant Human ASAH1 protein (ab114948)参考文献

ab114948 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab114948.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"